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Left Atrial Thrombus in Atrial Fibrillation/Flutter Patients in Relation to Anticoagulation Strategy: LATTEE Registry.
Kaplon-Cieslicka, Agnieszka; Gawalko, Monika; Budnik, Monika; Uzieblo-Zyczkowska, Beata; Krzesinski, Pawel; Starzyk, Katarzyna; Gorczyca-Glowacka, Iwona; Danilowicz-Szymanowicz, Ludmila; Kaufmann, Damian; Wójcik, Maciej; Blaszczyk, Robert; Hiczkiewicz, Jaroslaw; Lojewska, Katarzyna; Mizia-Stec, Katarzyna; Wybraniec, Maciej T; Kosmalska, Katarzyna; Fijalkowski, Marcin; Szymanska, Anna; Dluzniewski, Miroslaw; Haberka, Maciej; Kucio, Michal; Michalski, Blazej; Kupczynska, Karolina; Tomaszuk-Kazberuk, Anna; Wilk-Sledziewska, Katarzyna; Wachnicka-Truty, Renata; Kozinski, Marek; Burchardt, Pawel; Scislo, Piotr; Piatkowski, Radoslaw; Kochanowski, Janusz; Opolski, Grzegorz; Grabowski, Marcin.
Afiliação
  • Kaplon-Cieslicka A; "Club 30", Polish Cardiac Society, 02-097 Warsaw, Poland.
  • Gawalko M; 1st Department of Cardiology, Medical University of Warsaw, 02-097 Warsaw, Poland.
  • Budnik M; "Club 30", Polish Cardiac Society, 02-097 Warsaw, Poland.
  • Uzieblo-Zyczkowska B; 1st Department of Cardiology, Medical University of Warsaw, 02-097 Warsaw, Poland.
  • Krzesinski P; Institute of Pharmacology, West German Heart and Vascular Centre, University Duisburg-Essen, 45147 Essen, Germany.
  • Starzyk K; Department of Cardiology, Maastricht University Medical Centre and Cardiovascular Research Institute Maastricht, 6229 ER Maastricht, The Netherlands.
  • Gorczyca-Glowacka I; "Club 30", Polish Cardiac Society, 02-097 Warsaw, Poland.
  • Danilowicz-Szymanowicz L; 1st Department of Cardiology, Medical University of Warsaw, 02-097 Warsaw, Poland.
  • Kaufmann D; Department of Cardiology and Internal Diseases, Military Institute of Medicine, 01-755 Warsaw, Poland.
  • Wójcik M; "Club 30", Polish Cardiac Society, 02-097 Warsaw, Poland.
  • Blaszczyk R; Department of Cardiology and Internal Diseases, Military Institute of Medicine, 01-755 Warsaw, Poland.
  • Hiczkiewicz J; 1st Clinic of Cardiology and Electrotherapy, Swietokrzyskie Cardiology Centre, 25-558 Kielce, Poland.
  • Lojewska K; 1st Clinic of Cardiology and Electrotherapy, Swietokrzyskie Cardiology Centre, 25-558 Kielce, Poland.
  • Mizia-Stec K; Department of Cardiology and Electrotherapy, Medical University of Gdansk, 80-210 Gdansk, Poland.
  • Wybraniec MT; Department of Cardiology and Electrotherapy, Medical University of Gdansk, 80-210 Gdansk, Poland.
  • Kosmalska K; "Club 30", Polish Cardiac Society, 02-097 Warsaw, Poland.
  • Fijalkowski M; Department of Cardiology, Medical University of Lublin, 20-059 Lublin, Poland.
  • Szymanska A; Department of Cardiology, Medical University of Lublin, 20-059 Lublin, Poland.
  • Dluzniewski M; Collegium Medicum, University of Zielona Góra, 65-417 Zielona Gora, Poland.
  • Haberka M; Clinical Department of Cardiology, Nowa Sól Multidisciplinary Hospital, 67-100 Nowa Sol, Poland.
  • Kucio M; Clinical Department of Cardiology, Nowa Sól Multidisciplinary Hospital, 67-100 Nowa Sol, Poland.
  • Michalski B; "Club 30", Polish Cardiac Society, 02-097 Warsaw, Poland.
  • Kupczynska K; 1st Department of Cardiology, School of Medicine in Katowice, Medical University of Silesia, 40-055 Katowice, Poland.
  • Tomaszuk-Kazberuk A; "Club 30", Polish Cardiac Society, 02-097 Warsaw, Poland.
  • Wilk-Sledziewska K; 1st Department of Cardiology, School of Medicine in Katowice, Medical University of Silesia, 40-055 Katowice, Poland.
  • Wachnicka-Truty R; Department of Cardiology, St. Vincent Hospital, 81-348 Gdynia, Poland.
  • Kozinski M; "Club 30", Polish Cardiac Society, 02-097 Warsaw, Poland.
  • Burchardt P; 1st Department of Cardiology, Medical University of Gdansk, 80-210 Gdansk, Poland.
  • Scislo P; "Club 30", Polish Cardiac Society, 02-097 Warsaw, Poland.
  • Piatkowski R; Department of Heart Diseases, Postgraduate Medical School, 00-002 Warsaw, Poland.
  • Kochanowski J; Department of Heart Diseases, Postgraduate Medical School, 00-002 Warsaw, Poland.
  • Opolski G; "Club 30", Polish Cardiac Society, 02-097 Warsaw, Poland.
  • Grabowski M; Department of Cardiology, School of Health Sciences, Medical University of Silesia, 40-055 Katowice, Poland.
J Clin Med ; 11(10)2022 May 11.
Article em En | MEDLINE | ID: mdl-35628832
Background: Atrial fibrillation (AF) and flutter (AFl) increase the risk of thromboembolism. The aim of the study was to assess the prevalence of left atrial thrombus (LAT) in AF/AFl in relation to oral anticoagulation (OAC). Methods: LATTEE (NCT03591627) was a multicenter, prospective, observational study enrolling consecutive patients with AF/AFl referred for transesophageal echocardiography before cardioversion or ablation. Results: Of 3109 patients enrolled, 88% were on chronic, 1.5% on transient OAC and 10% without OAC. Of patients on chronic OAC, 39% received rivaroxaban, 30% dabigatran, 14% apixaban and 18% vitamin K antagonists (VKA). Patients on apixaban were oldest, had the worst renal function and were highest in both bleeding and thromboembolic risk, and more often received reduced doses. Prevalence of LAT was 8.0% (7.3% on chronic OAC vs. 15% without OAC; p < 0.01). In patients on VKA, prevalence of LAT was doubled compared to patients on non-VKA-OACs (NOACs) (13% vs. 6.0%; p < 0.01), even after propensity score weighting (13% vs. 7.5%; p < 0.01). Prevalence of LAT in patients on apixaban was higher (9.8%) than in those on rivaroxaban (5.7%) and dabigatran (4.7%; p < 0.01 for both comparisons), however, not after propensity score weighting. Conclusions: The prevalence of LAT in AF is non-negligible even on chronic OAC. The risk of LAT seems higher on VKA compared to NOAC, and similar between different NOACs.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials / Observational_studies / Risk_factors_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials / Observational_studies / Risk_factors_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article