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Inflammatory auto-immune diseases of the intestine and their management by natural bioactive compounds.
El Menyiy, Naoual; El Allam, Aicha; Aboulaghras, Sara; Jaouadi, Imane; Bakrim, Saad; El Omari, Nasreddine; Shariati, Mohammad Ali; Miftakhutdinov, Alevtin; Wilairatana, Polrat; Mubarak, Mohammad S; Bouyahya, Abdelhakim.
Afiliação
  • El Menyiy N; Laboratory of Pharmacology, National Agency of Medicinal and Aromatic Plants, 34025 Taounate, Morocco. Electronic address: naoualelmenyiy@gmail.com.
  • El Allam A; Laboratory of Human Pathologies Biology, Department of Biology, Faculty of Sciences, Mohammed V University in Rabat, Morocco. Electronic address: elallamaicha@gmail.com.
  • Aboulaghras S; Physiology and Physiopathology Team, Department of Biology, Mohammed V University in Rabat, Morocco. Electronic address: sara.aboulghras@gmail.com.
  • Jaouadi I; Laboratory of Organic Chemistry, Catalysis and Environment, Department of Chemistry, Faculty of Sciences, Ibn Tofail University, B.P.133, Kenitra 14000, Morocco. Electronic address: jaouadi.imane@gmail.com.
  • Bakrim S; Molecular Engineering, Valorization and Environment Team, Polydisciplinary Faculty of Taroudant, Ibn Zohr University, Agadir, Morocco. Electronic address: s.bakrim@hotmail.com.
  • El Omari N; Laboratory of Histology, Embryology and Cytogenetic, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco. Electronic address: nasrelomari@gmail.com.
  • Shariati MA; Department of Scientific Research, K.G. Razumovsky Moscow State University of technologies and management (The First Cossack University), 73, Zemlyanoy Val St., Moscow 109004, Russian Federation. Electronic address: shariatymohammadali@gmail.com.
  • Miftakhutdinov A; Department of Morphology, Physiology and Pharmacology, South Ural State Agrarian University, 13 Gagarin str., Troitsk 457100, Russian Federation. Electronic address: nirugavm@mail.ru.
  • Wilairatana P; Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand. Electronic address: polrat.wil@mahidol.ac.th.
  • Mubarak MS; Department of Chemistry, The University of Jordan, Amman 11942, Jordan. Electronic address: mmubarak@ju.edu.jo.
  • Bouyahya A; Laboratory of Human Pathologies Biology, Department of Biology, Faculty of Sciences, Mohammed V University in Rabat, Morocco. Electronic address: boyahyaa-90@hotmail.fr.
Biomed Pharmacother ; 151: 113158, 2022 Jul.
Article em En | MEDLINE | ID: mdl-35644116
ABSTRACT
Autoimmune diseases are caused by the overactivity of the immune system towards self-constituents. Risk factors of autoimmune diseases are multiple and include genetic, epigenetic, environmental, and psychological. Autoimmune chronic inflammatory bowel diseases, including celiac and inflammatory diseases (Crohn's disease and ulcerative colitis), constitute a significant health problem worldwide. Besides the complexity of the symptoms of these diseases, their treatments have only been palliative. Numerous investigations showed that natural phytochemicals could be promising strategies to fight against these autoimmune diseases. In this respect, plant-derived natural compounds such as flavonoids, phenolic acids, and terpenoids exhibited significant effects against three autoimmune diseases affecting the intestine, particularly bowel diseases. This review focuses on the role of natural compounds obtained from medicinal plants in modulating inflammatory auto-immune diseases of the intestine. It covers the most recent literature related to the effect of these natural compounds in the treatment and prevention of auto-immune diseases of the intestine.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Doenças Inflamatórias Intestinais / Colite Ulcerativa / Doença de Crohn Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Doenças Inflamatórias Intestinais / Colite Ulcerativa / Doença de Crohn Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article