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Discovery and characterization of a potent activator of the BKCa channel that relives overactive bladder syndrome in rats.
Jo, Heeji; Bae, Eun Jung; Lee, Narasaem; Kwon, Jae Won; Cho, Suhan; Kim, Sung Joon; Ahn, Jin Hee; Park, Chul-Seung.
Afiliação
  • Jo H; School of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju, 61005, Republic of Korea; Center for AI-applied High Efficiency Drug Discovery, Gwangju Institute of Science and Technology (GIST), Gwangju, 61005, Republic of Korea.
  • Bae EJ; Department of Chemistry, Gwangju Institute of Science and Technology (GIST), Gwangju, 61005, Republic of Korea.
  • Lee N; School of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju, 61005, Republic of Korea; Center for AI-applied High Efficiency Drug Discovery, Gwangju Institute of Science and Technology (GIST), Gwangju, 61005, Republic of Korea.
  • Kwon JW; Department of Physiology, Seoul National University, Seoul, 03080, Republic of Korea.
  • Cho S; Department of Physiology, Seoul National University, Seoul, 03080, Republic of Korea.
  • Kim SJ; Department of Physiology, Seoul National University, Seoul, 03080, Republic of Korea; Ischemic/Hypoxic Disease Institute, Seoul National University, Seoul, 03080, Republic of Korea.
  • Ahn JH; Department of Chemistry, Gwangju Institute of Science and Technology (GIST), Gwangju, 61005, Republic of Korea.
  • Park CS; School of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju, 61005, Republic of Korea; Center for AI-applied High Efficiency Drug Discovery, Gwangju Institute of Science and Technology (GIST), Gwangju, 61005, Republic of Korea. Electronic address: cspark@gist.ac.kr.
Eur J Pharmacol ; 927: 175055, 2022 Jul 15.
Article em En | MEDLINE | ID: mdl-35644420
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bexiga Urinária Hiperativa Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bexiga Urinária Hiperativa Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article