Injectable alginate hydrogels for synergistic tumor combination therapy through repolarization of tumor-associated macrophages.

Xiao, Tingting; Zhu, Jianzhi; Jia, Liang; Che, Hailong; Liu, Jie; Deckers, J; van Hest, Jan C M; Shi, Xiangyang

Xiao, Tingting; Zhu, Jianzhi; Jia, Liang; Che, Hailong; Liu, Jie; Deckers, J; van Hest, Jan C M; Shi, Xiangyang.

Afiliação

Xiao T; State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, People's Republic of China.
Zhu J; State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, People's Republic of China; Bio-Organic Chemistry, Institute for Complex Molecular Systems, Eindhoven University of Techn
Jia L; State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, People's Republic of China.
Che H; Bio-Organic Chemistry, Institute for Complex Molecular Systems, Eindhoven University of Technology, 5600 MB Eindhoven, the Netherlands.
Liu J; Bio-Organic Chemistry, Institute for Complex Molecular Systems, Eindhoven University of Technology, 5600 MB Eindhoven, the Netherlands.
Deckers J; Bio-Organic Chemistry, Institute for Complex Molecular Systems, Eindhoven University of Technology, 5600 MB Eindhoven, the Netherlands.
van Hest JCM; Bio-Organic Chemistry, Institute for Complex Molecular Systems, Eindhoven University of Technology, 5600 MB Eindhoven, the Netherlands. Electronic address: j.c.m.v.hest@tue.nl.
Shi X; State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, People's Republic of China. Electronic address: xshi@dhu.edu.cn.

J Control Release ; 348: 239-249, 2022 08.

Article em En | MEDLINE | ID: mdl-35660633

Assuntos

Hidrogéis; Neoplasias; Alginatos; Linhagem Celular Tumoral; Glucose/metabolismo; Glucose Oxidase; Humanos; Peróxido de Hidrogênio/metabolismo; Neoplasias/metabolismo; Macrófagos Associados a Tumor

Palavras-chave

Combination therapy; Ferromagnetic nanoparticles; Glucose oxidase; Injectable hydrogels; Resiquimod; Tumor-associated macrophages repolarization

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hidrogéis / Neoplasias Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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