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Plasma flow chemistry for direct N-acylation of amines by esters.
Abedelnour, Elias; Ognier, Stephanie; Zhang, Mengxue; Schio, Laurent; Venier, Olivier; Cossy, Janine; Tatoulian, Michael.
Afiliação
  • Abedelnour E; Chimie Paristech, PSL University, CNRS, Institut de Recherche de Chimie Paris, UMR8247, 11 rue Pierre et Marie Curie, 75005 - Paris, France. michael.tatoulian@chimieparistech.psl.eu.
  • Ognier S; Sanofi, Integrated Drug Discovery - IDD France, 1 Avenue Pierre Brossolette - Chilly Mazarin, France.
  • Zhang M; Chimie Paristech, PSL University, CNRS, Institut de Recherche de Chimie Paris, UMR8247, 11 rue Pierre et Marie Curie, 75005 - Paris, France. michael.tatoulian@chimieparistech.psl.eu.
  • Schio L; Chimie Paristech, PSL University, CNRS, Institut de Recherche de Chimie Paris, UMR8247, 11 rue Pierre et Marie Curie, 75005 - Paris, France. michael.tatoulian@chimieparistech.psl.eu.
  • Venier O; Sanofi, Integrated Drug Discovery - IDD France, 1 Avenue Pierre Brossolette - Chilly Mazarin, France.
  • Cossy J; Sanofi, Integrated Drug Discovery - IDD France, 1 Avenue Pierre Brossolette - Chilly Mazarin, France.
  • Tatoulian M; Molecular, Macromolecular Chemistry and Materials (C3M), ESPCI Paris, PSL University, CNRS, 75005 - Paris, France. janine.cossy@espci.fr.
Chem Commun (Camb) ; 58(52): 7281-7284, 2022 Jun 28.
Article em En | MEDLINE | ID: mdl-35678143
ABSTRACT
The direct N-acylation of amines by esters in a microreactor is described using argon plasma, thereby producing amides in good to excellent yields.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ésteres / Aminas Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ésteres / Aminas Idioma: En Ano de publicação: 2022 Tipo de documento: Article