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Identification of PRMT5 inhibitors with novel scaffold structures through virtual screening and biological evaluations.
Zhang, Qian; Zhang, Lun; Jin, Jia; Fan, Yaohua; Wang, Xiaoguang; Hu, Haofeng; Ye, Xiaoqing; Wang, Lei; Cao, Chenxi; Ye, Fei.
Afiliação
  • Zhang Q; College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, China.
  • Zhang L; College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, China.
  • Jin J; College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, China.
  • Fan Y; Department of Surgery, The Second Affiliated Hospital of Jia Xing University, Jiaxing, China.
  • Wang X; Department of Surgery, The Second Affiliated Hospital of Jia Xing University, Jiaxing, China.
  • Hu H; College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, China.
  • Ye X; College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, China.
  • Wang L; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materta Medica, Chinese Academy of Sciences, Shanghai, China.
  • Cao C; College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, China.
  • Ye F; Department of Surgery, The Second Affiliated Hospital of Jia Xing University, Jiaxing, China. jxeycaochenxi@163.com.
J Mol Model ; 28(7): 184, 2022 Jun 10.
Article em En | MEDLINE | ID: mdl-35680707
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína-Arginina N-Metiltransferases / Inibidores Enzimáticos Tipo de estudo: Diagnostic_studies / Screening_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína-Arginina N-Metiltransferases / Inibidores Enzimáticos Tipo de estudo: Diagnostic_studies / Screening_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article