PCDH17 is regulated by methylation of DNMT3B and affects the malignant biological behavior of HCC through EMT.

Liu, Yan; Zhang, Yudi; Du, Di; Gu, Xue; Zhou, Shiji

Liu, Yan; Zhang, Yudi; Du, Di; Gu, Xue; Zhou, Shiji.

Afiliação

Liu Y; Department of Gastroenterology, The Fifth People's Hospital of Chengdu, Sichuan, China.
Zhang Y; Department of Gastroenterology, The Fifth People's Hospital of Chengdu, Sichuan, China.
Du D; Department of Gastroenterology, The Fifth People's Hospital of Chengdu, Sichuan, China.
Gu X; Department of Gastroenterology, The Fifth People's Hospital of Chengdu, Sichuan, China.
Zhou S; Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China. Electronic address: zhoushiji@hospital.cqmu.edu.cn.

Exp Cell Res ; 418(1): 113245, 2022 09 01.

Article em En | MEDLINE | ID: mdl-35688280

Assuntos

Carcinoma Hepatocelular; Neoplasias Hepáticas; Caderinas/genética; Caderinas/metabolismo; Carcinoma Hepatocelular/patologia; Linhagem Celular Tumoral; Proliferação de Células/genética; Metilação de DNA/genética; Regulação Neoplásica da Expressão Gênica/genética; Humanos; Neoplasias Hepáticas/patologia; Regiões Promotoras Genéticas

Palavras-chave

DNMT3B; EMT; HCC; Malignant biological behavior; Methylation; PCDH17

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Neoplasias Hepáticas Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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