[The research progress of mesenchymal stem cell induction and differentiation into corneal tissue].
Zhonghua Yan Ke Za Zhi
; 58(6): 461-466, 2022 Jun 11.
Article
em Zh
| MEDLINE
| ID: mdl-35692030
ABSTRACT
Keratopathy is one of the most important blinding eye diseases in the world. Corneal opacity caused by keratopathy can seriously damage visual function. For example, corneal ulcer can lead to perforation and even loss of the eyeball. Although corneal transplantation is a routine treatment in clinical practice, there are not only a serious shortage of corneal donors in our country, but also various complications after keratoplasty that can not be avoided. In recent years, with the rapid development of regenerative medicine, it has been found that mesenchymal stem cells can differentiate into a variety of functional cells including corneal tissue under suitable induction conditions, which has a broad prospect of clinical application. This finding provides new ideas and methods for the treatment of keratopathy and corneal blindness in many aspects. This article reviews the research status of induction methods of mesenchymal stem cells in various specialties, particularly in the corneal subspecialty.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transplante de Córnea
/
Doenças da Córnea
/
Opacidade da Córnea
/
Células-Tronco Mesenquimais
Limite:
Humans
Idioma:
Zh
Ano de publicação:
2022
Tipo de documento:
Article