Anti-inflammatory abietanes diterpenes and triterpenoids isolated from Clinopodium polycephalum.
Fitoterapia
; 161: 105244, 2022 Sep.
Article
em En
| MEDLINE
| ID: mdl-35728706
ABSTRACT
Two previously undescribed diterpenes (1 and 2), as well as one curious triterpenoid were isolated from Clinopodium polycephalum, a medicinal plant distributed in southwestern and eastern China. Their structures were elucidated using MS analyses, UV spectrum, and extensive 2D-homo and heteronuclear NMR data interpretations. Among them, 1 had an unusual skeletal characteristic produced by a rare methyl migration pathway. All monomer compounds exhibited inhibitory effects on NO production in LPS-induced RAW 264.7 cells without affecting cell viabilities, which were comparable to that of positive control.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Triterpenos
/
Lamiaceae
/
Diterpenos
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article