Enhanced healing efficacy of an optimized gabapentin-melittin nanoconjugate gel-loaded formulation in excised wounds of diabetic rats.

Asfour, Hani Z; Alhakamy, Nabil A; Ahmed, Osama A A; Fahmy, Usama A; Md, Shadab; El-Moselhy, Mohamed A; Rizg, Waleed Y; Alghaith, Adel F; Eid, Basma G; Abdel-Naim, Ashraf B

Asfour, Hani Z; Alhakamy, Nabil A; Ahmed, Osama A A; Fahmy, Usama A; Md, Shadab; El-Moselhy, Mohamed A; Rizg, Waleed Y; Alghaith, Adel F; Eid, Basma G; Abdel-Naim, Ashraf B.

Afiliação

Asfour HZ; Department of Medical Microbiology and Parasitology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Alhakamy NA; Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.
Ahmed OAA; Center of Excellence for Drug Research and Pharmaceutical Industries, King Abdulaziz University, Jeddah, Saudi Arabia.
Fahmy UA; Mohamed Saeed Tamer Chair for Pharmaceutical Industries, King Abdulaziz University, Jeddah, Saudi Arabia.
Md S; Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.
El-Moselhy MA; Center of Excellence for Drug Research and Pharmaceutical Industries, King Abdulaziz University, Jeddah, Saudi Arabia.
Rizg WY; Mohamed Saeed Tamer Chair for Pharmaceutical Industries, King Abdulaziz University, Jeddah, Saudi Arabia.
Alghaith AF; Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.
Eid BG; Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.
Abdel-Naim AB; Department of Clinical Pharmacy and Pharmacology, Ibn Sina National College for Medical Studies, Jeddah, Saudi Arabia.

Drug Deliv ; 29(1): 1892-1902, 2022 Dec.

Article em En | MEDLINE | ID: mdl-35748413

Assuntos

Diabetes Mellitus Experimental; Fator A de Crescimento do Endotélio Vascular; Animais; Anti-Inflamatórios/uso terapêutico; Antioxidantes/metabolismo; Colágeno/metabolismo; Diabetes Mellitus Experimental/metabolismo; Gabapentina/metabolismo; Gabapentina/uso terapêutico; Meliteno/metabolismo; Meliteno/uso terapêutico; Nanoconjugados/uso terapêutico; Ratos; Ratos Wistar; Pele/metabolismo; Fator A de Crescimento do Endotélio Vascular/metabolismo; Cicatrização

Palavras-chave

Diabetes; gabapentin; melittin; nanoconjugation; wound healing

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator A de Crescimento do Endotélio Vascular / Diabetes Mellitus Experimental Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google