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Early expression of mature αß TCR in CD4-CD8- T cell progenitors enables MHC to drive development of T-ALL bearing NOTCH mutations.
Laffey, Kimberly G; Stiles, Robert J; Ludescher, Melissa J; Davis, Tessa R; Khwaja, Shariq S; Bram, Richard J; Wettstein, Peter J; Ramachandran, Venkataraman; Parks, Christopher A; Reyes, Edwin E; Ferrer, Alejandro; Canfield, Jenna M; Johnson, Cory E; Hammer, Richard D; Gil, Diana; Schrum, Adam G.
Afiliação
  • Laffey KG; Department of Molecular Microbiology & Immunology, School of Medicine, University of Missouri-Columbia, Columbia, MO 65212.
  • Stiles RJ; Department of Immunology, Mayo Clinic College of Medicine, Rochester, MN 55095.
  • Ludescher MJ; Department of Immunology, Mayo Clinic College of Medicine, Rochester, MN 55095.
  • Davis TR; Department of Immunology, Mayo Clinic College of Medicine, Rochester, MN 55095.
  • Khwaja SS; Department of Immunology, Mayo Clinic College of Medicine, Rochester, MN 55095.
  • Bram RJ; Department of Immunology, Mayo Clinic College of Medicine, Rochester, MN 55095.
  • Wettstein PJ; Department of Pediatrics, Mayo Clinic College of Medicine, Rochester, MN 55095.
  • Ramachandran V; Department of Immunology, Mayo Clinic College of Medicine, Rochester, MN 55095.
  • Parks CA; Department of Surgery, Mayo Clinic College of Medicine, Rochester, MN 55095.
  • Reyes EE; Department of Surgery, School of Medicine, University of Missouri-Columbia, Columbia, MO 65212.
  • Ferrer A; Department of Immunology, Mayo Clinic College of Medicine, Rochester, MN 55095.
  • Canfield JM; Department of Immunology, Mayo Clinic College of Medicine, Rochester, MN 55095.
  • Johnson CE; Department of Immunology, Mayo Clinic College of Medicine, Rochester, MN 55095.
  • Hammer RD; Department of Molecular Microbiology & Immunology, School of Medicine, University of Missouri-Columbia, Columbia, MO 65212.
  • Gil D; Clinical Flow Cytometry Laboratory, University Hospital, University of Missouri-Columbia, Columbia, MO 65212.
  • Schrum AG; Clinical Flow Cytometry Laboratory, University Hospital, University of Missouri-Columbia, Columbia, MO 65212.
Proc Natl Acad Sci U S A ; 119(27): e2118529119, 2022 07 05.
Article em En | MEDLINE | ID: mdl-35767640
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Antígenos de Linfócitos T alfa-beta / Linfócitos T CD8-Positivos / Receptor Notch1 / Leucemia-Linfoma Linfoblástico de Células T Precursoras Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Antígenos de Linfócitos T alfa-beta / Linfócitos T CD8-Positivos / Receptor Notch1 / Leucemia-Linfoma Linfoblástico de Células T Precursoras Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article