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Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects.
Robertson, Neil A; Latorre-Crespo, Eric; Terradas-Terradas, Maria; Lemos-Portela, Jorge; Purcell, Alison C; Livesey, Benjamin J; Hillary, Robert F; Murphy, Lee; Fawkes, Angie; MacGillivray, Louise; Copland, Mhairi; Marioni, Riccardo E; Marsh, Joseph A; Harris, Sarah E; Cox, Simon R; Deary, Ian J; Schumacher, Linus J; Kirschner, Kristina; Chandra, Tamir.
Afiliação
  • Robertson NA; MRC Human Genetics Unit, University of Edinburgh, Edinburgh, UK.
  • Latorre-Crespo E; MRC Human Genetics Unit, University of Edinburgh, Edinburgh, UK.
  • Terradas-Terradas M; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
  • Lemos-Portela J; Cancer Research UK Beatson Institute, Glasgow, UK.
  • Purcell AC; Centre for Regenerative Medicine, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK.
  • Livesey BJ; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
  • Hillary RF; Cancer Research UK Beatson Institute, Glasgow, UK.
  • Murphy L; MRC Human Genetics Unit, University of Edinburgh, Edinburgh, UK.
  • Fawkes A; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
  • MacGillivray L; Edinburgh Clinical Research Facility, University of Edinburgh, Edinburgh, UK.
  • Copland M; Edinburgh Clinical Research Facility, University of Edinburgh, Edinburgh, UK.
  • Marioni RE; Edinburgh Clinical Research Facility, University of Edinburgh, Edinburgh, UK.
  • Marsh JA; Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
  • Harris SE; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
  • Cox SR; MRC Human Genetics Unit, University of Edinburgh, Edinburgh, UK.
  • Deary IJ; Lothian Birth Cohorts, Department of Psychology, University of Edinburgh, Edinburgh, UK.
  • Schumacher LJ; Lothian Birth Cohorts, Department of Psychology, University of Edinburgh, Edinburgh, UK.
  • Kirschner K; Lothian Birth Cohorts, Department of Psychology, University of Edinburgh, Edinburgh, UK.
  • Chandra T; Centre for Regenerative Medicine, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK. linus.schumacher@ed.ac.uk.
Nat Med ; 28(7): 1439-1446, 2022 07.
Article em En | MEDLINE | ID: mdl-35788175
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia / Hematopoese Tipo de estudo: Risk_factors_studies Limite: Humans / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia / Hematopoese Tipo de estudo: Risk_factors_studies Limite: Humans / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article