Synthesis and Biological Evaluation of Novel Phthalide Analogs-1,2,4-Oxadiazole Hybrids as Potential Anti-Inflammatory Agents.

Ruan, Banfeng; Tang, Xiaofei; Guo, Weiyun; Hu, Yong; Chen, Liuzeng

Ruan, Banfeng; Tang, Xiaofei; Guo, Weiyun; Hu, Yong; Chen, Liuzeng.

Afiliação

Ruan B; Key Lab of Biofabrication of Anhui Higher Education, Hefei University, Hefei, 230601, P. R. China.
Tang X; Key Lab of Biofabrication of Anhui Higher Education, Hefei University, Hefei, 230601, P. R. China.
Guo W; Key Lab of Biofabrication of Anhui Higher Education, Hefei University, Hefei, 230601, P. R. China.
Hu Y; Agro-products Processing Research Institute, Anhui Academy of Agricultural Sciences, Hefei, 230001, P. R. China.
Chen L; Key Lab of Biofabrication of Anhui Higher Education, Hefei University, Hefei, 230601, P. R. China.

Chem Biodivers ; 19(8): e202200039, 2022 Aug.

Article em En | MEDLINE | ID: mdl-35794072

Assuntos

Benzofuranos; Oxidiazóis; Animais; Anti-Inflamatórios/farmacologia; Lipopolissacarídeos/farmacologia; Camundongos; NF-kappa B/metabolismo; Óxido Nítrico/metabolismo; Óxido Nítrico Sintase Tipo II/metabolismo; Oxidiazóis/farmacologia; Células RAW 264.7

Palavras-chave

1,2,4-oxadiazole; SAR; anti-inflammatory activity; hybrids; phthalide derivatives

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxidiazóis / Benzofuranos Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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