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Transcription-associated DNA DSBs activate p53 during hiPSC-based neurogenesis.
Michel, Nadine; Young, Heather M Raimer; Atkin, Naomi D; Arshad, Umar; Al-Humadi, Reem; Singh, Sandeep; Manukyan, Arkadi; Gore, Lana; Burbulis, Ian E; Wang, Yuh-Hwa; McConnell, Michael J.
Afiliação
  • Michel N; Neuroscience Graduate Program, University of Virginia School of Medicine, 1340 Jefferson Park Avenue, Charlottesville, VA, 22908, USA.
  • Young HMR; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, 1340 Jefferson Park Avenue, Charlottesville, VA, 22908, USA.
  • Atkin ND; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, 1340 Jefferson Park Avenue, Charlottesville, VA, 22908, USA.
  • Arshad U; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, 1340 Jefferson Park Avenue, Charlottesville, VA, 22908, USA.
  • Al-Humadi R; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, 1340 Jefferson Park Avenue, Charlottesville, VA, 22908, USA.
  • Singh S; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, 1340 Jefferson Park Avenue, Charlottesville, VA, 22908, USA.
  • Manukyan A; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, 1340 Jefferson Park Avenue, Charlottesville, VA, 22908, USA.
  • Gore L; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, 1340 Jefferson Park Avenue, Charlottesville, VA, 22908, USA.
  • Burbulis IE; Lieber Institute for Brain Development, 855 N. Wolfe St., Ste. 300, Baltimore, MD, 21205, USA.
  • Wang YH; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, 1340 Jefferson Park Avenue, Charlottesville, VA, 22908, USA.
  • McConnell MJ; Sede de la Patagonia, Facultad de Medicina y Ciencias, Universidad San Sebastián, Puerto Montt, Chile.
Sci Rep ; 12(1): 12156, 2022 07 15.
Article em En | MEDLINE | ID: mdl-35840793
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quebras de DNA de Cadeia Dupla / Neurogênese / Células-Tronco Pluripotentes Induzidas Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quebras de DNA de Cadeia Dupla / Neurogênese / Células-Tronco Pluripotentes Induzidas Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article