LncRNA MINCR attenuates osteoarthritis progression via sponging miR-146a-5p to promote BMPR2 expression.

Li, Dongyun; Wang, Xiaoying; Yi, Tengda; Zhang, Lin; Feng, Lirui; Zhang, Mingxing; He, Yongsheng; Gang, Shunkui

Li, Dongyun; Wang, Xiaoying; Yi, Tengda; Zhang, Lin; Feng, Lirui; Zhang, Mingxing; He, Yongsheng; Gang, Shunkui.

Afiliação

Li D; Department of Preventive Treatment of Disease, the Third Affiliated Hospital of Yunnan University of Traditional Chinese Medicine, Kunming, China.
Wang X; Department of Preventive Treatment of Disease, the Third Affiliated Hospital of Yunnan University of Traditional Chinese Medicine, Kunming, China.
Yi T; Department of Preventive Treatment of Disease, the Third Affiliated Hospital of Yunnan University of Traditional Chinese Medicine, Kunming, China.
Zhang L; Department of Preventive Treatment of Disease, the Third Affiliated Hospital of Yunnan University of Traditional Chinese Medicine, Kunming, China.
Feng L; Department of Preventive Treatment of Disease, the Third Affiliated Hospital of Yunnan University of Traditional Chinese Medicine, Kunming, China.
Zhang M; Department of Preventive Treatment of Disease, the Third Affiliated Hospital of Yunnan University of Traditional Chinese Medicine, Kunming, China.
He Y; Research and development center, The Yunnan Labreal Biotechnology Co., Ltd, Kunming, China.
Gang S; Department of Preventive Treatment of Disease, the Third Affiliated Hospital of Yunnan University of Traditional Chinese Medicine, Kunming, China.

Cell Cycle ; 21(22): 2417-2432, 2022 Nov.

Article em En | MEDLINE | ID: mdl-35848848

Assuntos

MicroRNAs; Osteoartrite; RNA Longo não Codificante; Ratos; Animais; RNA Longo não Codificante/metabolismo; Receptores de Proteínas Morfogenéticas Ósseas Tipo II/genética; Receptores de Proteínas Morfogenéticas Ósseas Tipo II/metabolismo; Agrecanas/genética; Agrecanas/metabolismo; Agrecanas/farmacologia; Hibridização in Situ Fluorescente; MicroRNAs/genética; MicroRNAs/metabolismo; Osteoartrite/metabolismo; Condrócitos/metabolismo; Interleucina-1beta/metabolismo; Apoptose/genética

Palavras-chave

BMPR2; MINCR; Osteoarthritis; inflammation; miR-146a-5p

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite / MicroRNAs / RNA Longo não Codificante Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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