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Proton transfer activity of the reconstituted Mycobacterium tuberculosis MmpL3 is modulated by substrate mimics and inhibitors.
Stevens, Casey M; Babii, Svitlana O; Pandya, Amitkumar N; Li, Wei; Li, Yupeng; Mehla, Jitender; Scott, Robyn; Hegde, Pooja; Prathipati, Pavan K; Acharya, Atanu; Liu, Jinchan; Gumbart, James C; North, Jeffrey; Jackson, Mary; Zgurskaya, Helen I.
Afiliação
  • Stevens CM; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019.
  • Babii SO; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019.
  • Pandya AN; School of Pharmacy & Health Professions, Department of Pharmacy Sciences, Creighton University, Omaha, NE 68178.
  • Li W; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523.
  • Li Y; College of Chemistry, Jilin University, 130012 Changchun, China.
  • Mehla J; Tang Aoqing Honors Program in Science, Jilin University, 130012 Changchun, China.
  • Scott R; School of Physics, Georgia Institute of Technology, Atlanta, GA 30332.
  • Hegde P; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019.
  • Prathipati PK; School of Pharmacy & Health Professions, Department of Pharmacy Sciences, Creighton University, Omaha, NE 68178.
  • Acharya A; School of Pharmacy & Health Professions, Department of Pharmacy Sciences, Creighton University, Omaha, NE 68178.
  • Liu J; School of Pharmacy & Health Professions, Department of Pharmacy Sciences, Creighton University, Omaha, NE 68178.
  • Gumbart JC; School of Physics, Georgia Institute of Technology, Atlanta, GA 30332.
  • North J; College of Chemistry, Jilin University, 130012 Changchun, China.
  • Jackson M; Tang Aoqing Honors Program in Science, Jilin University, 130012 Changchun, China.
  • Zgurskaya HI; School of Physics, Georgia Institute of Technology, Atlanta, GA 30332.
Proc Natl Acad Sci U S A ; 119(30): e2113963119, 2022 07 26.
Article em En | MEDLINE | ID: mdl-35858440
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Membrana Transportadoras / Proteínas de Bactérias Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Membrana Transportadoras / Proteínas de Bactérias Idioma: En Ano de publicação: 2022 Tipo de documento: Article