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Mitochondria-targeted anti-oxidant AntiOxCIN4 improved liver steatosis in Western diet-fed mice by preventing lipid accumulation due to upregulation of fatty acid oxidation, quality control mechanism and antioxidant defense systems.
Amorim, Ricardo; Simões, Inês C M; Teixeira, José; Cagide, Fernando; Potes, Yaiza; Soares, Pedro; Carvalho, Adriana; Tavares, Ludgero C; Benfeito, Sofia; Pereira, Susana P; Simões, Rui F; Karkucinska-Wieckowska, Agnieszka; Viegas, Ivan; Szymanska, Sylwia; Dabrowski, Michal; Janikiewicz, Justyna; Cunha-Oliveira, Teresa; Dobrzyn, Agnieszka; Jones, John G; Borges, Fernanda; Wieckowski, Mariusz R; Oliveira, Paulo J.
Afiliação
  • Amorim R; CNC-Center for Neuroscience and Cell Biology, CIBB - Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504, Coimbra, Portugal; CIQUP/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Portugal; PhD Programme in Experimental Biology and
  • Simões ICM; Nencki Institute of Experimental Biology of Polish Academy of Sciences, Warsaw, Poland.
  • Teixeira J; CNC-Center for Neuroscience and Cell Biology, CIBB - Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504, Coimbra, Portugal.
  • Cagide F; CIQUP/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Portugal.
  • Potes Y; Nencki Institute of Experimental Biology of Polish Academy of Sciences, Warsaw, Poland.
  • Soares P; CIQUP/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Portugal.
  • Carvalho A; CNC-Center for Neuroscience and Cell Biology, CIBB - Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504, Coimbra, Portugal; PhD Programme in Experimental Biology and Biomedicine (PDBEB), Institute for Interdisciplinary Research (IIIUC), University of Coimbra, 3030-7
  • Tavares LC; CNC-Center for Neuroscience and Cell Biology, CIBB - Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504, Coimbra, Portugal; CIVG - Vasco da Gama Research Center, University School Vasco da Gama - EUVG, 3020-210, Coimbra, Portugal.
  • Benfeito S; CIQUP/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Portugal.
  • Pereira SP; CNC-Center for Neuroscience and Cell Biology, CIBB - Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504, Coimbra, Portugal; Laboratory of Metabolism and Exercise (LametEx), Research Centre in Physical Activity, Health and Leisure (CIAFEL), Laboratory for Integrative
  • Simões RF; CNC-Center for Neuroscience and Cell Biology, CIBB - Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504, Coimbra, Portugal; PhD Programme in Experimental Biology and Biomedicine (PDBEB), Institute for Interdisciplinary Research (IIIUC), University of Coimbra, 3030-7
  • Karkucinska-Wieckowska A; Department of Pathology, The Children's Memorial Health Institute, Warsaw, Poland.
  • Viegas I; Centre for Functional Ecology, Department of Life Sciences, University of Coimbra, Coimbra, Portugal.
  • Szymanska S; Department of Pathology, The Children's Memorial Health Institute, Warsaw, Poland.
  • Dabrowski M; Nencki Institute of Experimental Biology of Polish Academy of Sciences, Warsaw, Poland.
  • Janikiewicz J; Nencki Institute of Experimental Biology of Polish Academy of Sciences, Warsaw, Poland.
  • Cunha-Oliveira T; CNC-Center for Neuroscience and Cell Biology, CIBB - Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504, Coimbra, Portugal.
  • Dobrzyn A; Nencki Institute of Experimental Biology of Polish Academy of Sciences, Warsaw, Poland.
  • Jones JG; CNC-Center for Neuroscience and Cell Biology, CIBB - Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504, Coimbra, Portugal.
  • Borges F; CIQUP/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Portugal. Electronic address: fborges@fc.up.pt.
  • Wieckowski MR; Nencki Institute of Experimental Biology of Polish Academy of Sciences, Warsaw, Poland. Electronic address: m.wieckowski@nencki.edu.pl.
  • Oliveira PJ; CNC-Center for Neuroscience and Cell Biology, CIBB - Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504, Coimbra, Portugal. Electronic address: pauloliv@cnc.uc.pt.
Redox Biol ; 55: 102400, 2022 Sep.
Article em En | MEDLINE | ID: mdl-35863265
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article