You shall not pass! Unveiling the barriers for cohesin-mediated loop extrusion.

Meyer-Nava, Silvia; Rivera-Mulia, Juan Carlos

Meyer-Nava, Silvia; Rivera-Mulia, Juan Carlos.

Afiliação

Meyer-Nava S; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota Medical School, Minneapolis, MN, USA; Stem Cell Institute, University of Minnesota Medical School, Minneapolis, MN, USA.
Rivera-Mulia JC; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota Medical School, Minneapolis, MN, USA; Stem Cell Institute, University of Minnesota Medical School, Minneapolis, MN, USA; Masonic Cancer Center, University of Minnesota Medical School, Minneapolis, MN, USA. Electronic address: riveramj@umn.edu.

Mol Cell ; 82(14): 2541-2543, 2022 07 21.

Article em En | MEDLINE | ID: mdl-35868255

ABSTRACT

ABSTRACT

Dequeker and colleagues performed elegant in vivo, in silico, and in vitro experiments to demonstrate that the MCM complex, an essential DNA replication factor, is an obstacle for the DNA loop formation by cohesin.

Assuntos

Proteínas de Ciclo Celular; Proteínas Cromossômicas não Histona; Proteínas de Ciclo Celular/genética; Núcleo Celular; Cromatina; Proteínas Cromossômicas não Histona/genética; Coesinas

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Cromossômicas não Histona / Proteínas de Ciclo Celular Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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