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In addition to its endosomal escape effect, platycodin D also synergizes with ribosomal inactivation protein to induce apoptosis in hepatoma cells through AKT and MAPK signaling pathways.
Lei, Jin; Zhao, Jian; Long, Meng-Yi-Chen; Cao, Xue-Wei; Wang, Fu-Jun.
Afiliação
  • Lei J; Department of Applied Biology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China.
  • Zhao J; Department of Applied Biology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China.
  • Long MY; Department of Applied Biology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China.
  • Cao XW; Department of Applied Biology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China. Electronic address: caoxw@ecust.edu.cn.
  • Wang FJ; New Drug R&D Center, Zhejiang Fonow Medicine Co., Ltd. 209 West Hulian Road, Dongyang, 322100, Zhejiang, China; Shanghai R&D Center for Standardization of Chinese Medicines, 1200 Cailun Road, Shanghai, 201203, China; Institute of Chinese Materia Medica, Shanghai University of Traditional Chi
Chem Biol Interact ; 364: 110058, 2022 Sep 01.
Article em En | MEDLINE | ID: mdl-35872048
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saponinas / Triterpenos / Carcinoma Hepatocelular / Neoplasias Hepáticas Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saponinas / Triterpenos / Carcinoma Hepatocelular / Neoplasias Hepáticas Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article