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CRISPR-mediated TGFBR2 knockout renders human ovarian cancer tumor-infiltrating lymphocytes resistant to TGF-ß signaling.
Fix, Samantha M; Forget, Marie-Andrée; Sakellariou-Thompson, Donastas; Wang, Yunfei; Griffiths, Tamara M; Lee, Minjung; Haymaker, Cara L; Dominguez, Ana Lucía; Basar, Rafet; Reyes, Christopher; Kumar, Sanjay; Meyer, Larissa A; Hwu, Patrick; Bernatchez, Chantale; Jazaeri, Amir A.
Afiliação
  • Fix SM; Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Forget MA; Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Sakellariou-Thompson D; Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Wang Y; Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Griffiths TM; Biologics Development, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Lee M; Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Haymaker CL; Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Dominguez AL; Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Basar R; Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Reyes C; Cell Biology R&D, Thermo Fisher Scientific, Carlsbad, California, USA.
  • Kumar S; Cell Biology R&D, Thermo Fisher Scientific, Carlsbad, California, USA.
  • Meyer LA; Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Hwu P; Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA Patrick.Hwu@moffitt.org.
  • Bernatchez C; Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Jazaeri AA; Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
J Immunother Cancer ; 10(7)2022 07.
Article em En | MEDLINE | ID: mdl-35882447

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Linfócitos do Interstício Tumoral Tipo de estudo: Guideline Limite: Female / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Linfócitos do Interstício Tumoral Tipo de estudo: Guideline Limite: Female / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article