Exosome from indoleamine 2,3-dioxygenase-overexpressing bone marrow mesenchymal stem cells accelerates repair process of ischemia/reperfusion-induced acute kidney injury by regulating macrophages polarization.

Xie, Xiangcheng; Yang, Xiu; Wu, Junxia; Tang, Shengjie; Yang, LiLi; Fei, Xiao; Wang, Ming

Xie, Xiangcheng; Yang, Xiu; Wu, Junxia; Tang, Shengjie; Yang, LiLi; Fei, Xiao; Wang, Ming.

Afiliação

Xie X; Department of Nephrology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, No. 261, Huansha Road, Hangzhou, 310006, Zhejiang, China.
Yang X; Department of Nephrology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, No. 261, Huansha Road, Hangzhou, 310006, Zhejiang, China.
Wu J; Department of Nephrology, School of Medicine, The Second Affiliated Hospital, Zhejiang University, Hangzhou, China.
Tang S; Department of Nephrology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, No. 261, Huansha Road, Hangzhou, 310006, Zhejiang, China.
Yang L; Department of Nephrology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, No. 261, Huansha Road, Hangzhou, 310006, Zhejiang, China.
Fei X; Department of Nephrology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, No. 261, Huansha Road, Hangzhou, 310006, Zhejiang, China.
Wang M; Department of Nephrology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, No. 261, Huansha Road, Hangzhou, 310006, Zhejiang, China. wangmingdoct@yeah.net.

Stem Cell Res Ther ; 13(1): 367, 2022 07 28.

Article em En | MEDLINE | ID: mdl-35902956

Assuntos

Injúria Renal Aguda; Exossomos; Células-Tronco Mesenquimais; Traumatismo por Reperfusão; Injúria Renal Aguda/patologia; Injúria Renal Aguda/terapia; Animais; Exossomos/patologia; Indolamina-Pirrol 2,3,-Dioxigenase/genética; Inflamação/patologia; Isquemia/patologia; Rim/patologia; Macrófagos/patologia; Células-Tronco Mesenquimais/patologia; Camundongos; Reperfusão; Traumatismo por Reperfusão/patologia; Traumatismo por Reperfusão/terapia

Palavras-chave

Acute kidney injury; Indoleamine 2,3-dioxygenase; Macrophage polarization; Mesenchymal stem cell-derived extracellular vesicles

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Traumatismo por Reperfusão / Exossomos / Injúria Renal Aguda / Células-Tronco Mesenquimais Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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