Ocrelizumab quantitation by liquid chromatography-tandem mass spectrometry.

Hallin, Erik I; Trætteberg Serkland, Trond; Myhr, Kjell-Morten; Grytten Torkildsen, Øivind; Skrede, Silje

Hallin, Erik I; Trætteberg Serkland, Trond; Myhr, Kjell-Morten; Grytten Torkildsen, Øivind; Skrede, Silje.

Afiliação

Hallin EI; Section of Clinical Pharmacology, Department of Medical Biochemistry and Pharmacology, Haukeland University Hospital, Jonas Lies Vei 87, N-5021 Bergen, Norway.
Trætteberg Serkland T; Section of Clinical Pharmacology, Department of Medical Biochemistry and Pharmacology, Haukeland University Hospital, Jonas Lies Vei 87, N-5021 Bergen, Norway.
Myhr KM; Department of Clinical Science, University of Bergen, Jonas Lies Vei 87, N-5021 Bergen, Norway.
Grytten Torkildsen Ø; Department of Clinical Medicine, University of Bergen, Jonas Lies Vei 87, N-5021 Bergen, Norway.
Skrede S; Neuro-SysMed, Department of Neurology, Haukeland University Hospital, Jonas Lies Vei 71, N-5053 Bergen, Norway.

J Mass Spectrom Adv Clin Lab ; 25: 53-60, 2022 Aug.

Article em En | MEDLINE | ID: mdl-35910410

Palavras-chave

EMA, European Medicines Agency; IDA, Information dependent acqusition; IgG1, immunoglobulin G1; LC-MS/MS; LC-MS/MS, Liquid chromatography-tandem mass spectrometry; MS, Multiple sclerosis; MWCO, molecular weight cut-off; Multiple sclerosis; OVERLORD-MS, Ocrelizumab vErsus Rituximab Off-Label at the Onset of Relapsing MS; Ocrelizumab; QTOF, quadrupole time-of-flight; QTRAP, quadrupole ion trap; ROS-MS, Rituximab and Ocrelizumab in Serum with Multiple Sclerosis study; TDM, therapeutic drug monitoring; Therapeutic drug monitoring; Therapeutic monoclonal antibodies; UHPLC, ultra high performance liquid chromatography; t-mAb, therapeutic monoclonal antibody

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article