The analgesic and anti-inflammatory efficacy of diflunisal and codeine after removal of impacted third molars.
Curr Med Res Opin
; 5(7): 525-35, 1978.
Article
em En
| MEDLINE
| ID: mdl-359245
ABSTRACT
A double-blind, randomized trial was carried out in 90 patients to compare the analgesic and anti-inflammatory efficacy of 500 mg diflunisal twice daily with that of 25 mg codeine phosphate 4-times daily and placebo in relieving pain and swelling after surgical removal of impacted third molars. Diflunisal was found to be superior to codeine and placebo on the first post-operative day, but the difference in efficacy of the drugs had diminished by the third post-operative day. In the diflunisal group of 30 patients, 10 (33%) developed 'dry socket' or alveolitis sicca dolorosa. Only 2 patients in the codeine group and 1 patient in the placebo group developed this very painful condition. The possible explanation of 'dry socket' is discussed.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Extração Dentária
/
Dente Impactado
/
Compostos de Bifenilo
/
Anti-Inflamatórios não Esteroides
/
Codeína
/
Analgésicos
/
Dente Molar
Tipo de estudo:
Clinical_trials
Limite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
1978
Tipo de documento:
Article