Methylene blue, Mycophenolic acid, Posaconazole, and Niclosamide inhibit SARS-CoV-2 Omicron variant BA.1 infection of human airway epithelial organoids.

Volle, Romain; Murer, Luca; Petkidis, Anthony; Andriasyan, Vardan; Savi, Alessandro; Bircher, Cornelia; Meili, Nicole; Fischer, Lucy; Sequeira, Daniela Policarpo; Mark, Daniela Katharina; Gomez-Gonzalez, Alfonso; Greber, Urs F

Volle, Romain; Murer, Luca; Petkidis, Anthony; Andriasyan, Vardan; Savi, Alessandro; Bircher, Cornelia; Meili, Nicole; Fischer, Lucy; Sequeira, Daniela Policarpo; Mark, Daniela Katharina; Gomez-Gonzalez, Alfonso; Greber, Urs F.

Afiliação

Volle R; Department of Molecular Life Sciences, University of Zürich, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
Murer L; Department of Molecular Life Sciences, University of Zürich, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
Petkidis A; Department of Molecular Life Sciences, University of Zürich, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
Andriasyan V; Life Science Zürich Graduate School, ETH and University of Zurich, 8057 Zurich, Switzerland.
Savi A; Department of Molecular Life Sciences, University of Zürich, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
Bircher C; Department of Molecular Life Sciences, University of Zürich, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
Meili N; Life Science Zürich Graduate School, ETH and University of Zurich, 8057 Zurich, Switzerland.
Fischer L; Department of Molecular Life Sciences, University of Zürich, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
Sequeira DP; Life Science Zürich Graduate School, ETH and University of Zurich, 8057 Zurich, Switzerland.
Mark DK; Department of Molecular Life Sciences, University of Zürich, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
Gomez-Gonzalez A; Department of Molecular Life Sciences, University of Zürich, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
Greber UF; Department of Molecular Life Sciences, University of Zürich, Winterthurerstrasse 190, 8057, Zurich, Switzerland.

Curr Res Microb Sci ; 3: 100158, 2022.

Article em En | MEDLINE | ID: mdl-35935678

Palavras-chave

Drug repurposing; HAEEC, Human airway epithelial explant culture; Human nasal and bronchial epithelial explant cultures; MB, Methylene Blue; MPA, Mycophenolic acid; Methylene blue; Mycophenolic acid; Niclo, Niclosamide; Niclosamide; POS, Posaconazole; Persistent infection; Posaconazole; SARS-CoV-2 variant of concern Omicron (BA.1); SARS-CoV-2, Severe acute respiratory syndrome coronavirus type 2; VoC, Variant of concern

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article