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Prohormone convertase 1/3 deficiency causes obesity due to impaired proinsulin processing.
Meier, Daniel T; Rachid, Leila; Wiedemann, Sophia J; Traub, Shuyang; Trimigliozzi, Kelly; Stawiski, Marc; Sauteur, Loïc; Winter, Denise V; Le Foll, Christelle; Brégère, Catherine; Guzman, Raphael; Odermatt, Alex; Böni-Schnetzler, Marianne; Donath, Marc Y.
Afiliação
  • Meier DT; Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland. daniel.zeman@unibas.ch.
  • Rachid L; Department of Biomedicine, University of Basel, Basel, Switzerland. daniel.zeman@unibas.ch.
  • Wiedemann SJ; Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland.
  • Traub S; Department of Biomedicine, University of Basel, Basel, Switzerland.
  • Trimigliozzi K; Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland.
  • Stawiski M; Department of Biomedicine, University of Basel, Basel, Switzerland.
  • Sauteur L; Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland.
  • Winter DV; Department of Biomedicine, University of Basel, Basel, Switzerland.
  • Le Foll C; Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland.
  • Brégère C; Department of Biomedicine, University of Basel, Basel, Switzerland.
  • Guzman R; Clinic of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Basel, Switzerland.
  • Odermatt A; Department of Biomedicine, University of Basel, Basel, Switzerland.
  • Böni-Schnetzler M; Department of Biomedicine, University of Basel, Basel, Switzerland.
  • Donath MY; Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.
Nat Commun ; 13(1): 4761, 2022 08 13.
Article em En | MEDLINE | ID: mdl-35963866
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proinsulina / Diabetes Mellitus Tipo de estudo: Etiology_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proinsulina / Diabetes Mellitus Tipo de estudo: Etiology_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article