Polyethylene glycol 20 kDa-induced vacuolation does not impair phagocytic function of human monocyte-derived macrophages.

Schoenbrunn, Anne; Juelke, Kerstin; Reipert, Birgit M; Horling, Frank; Turecek, Peter L

Schoenbrunn, Anne; Juelke, Kerstin; Reipert, Birgit M; Horling, Frank; Turecek, Peter L.

Afiliação

Schoenbrunn A; BIH Center for Regenerative Therapies and Institute of Medical Immunology, Charité Universitätsmedizin, Berlin, Germany.
Juelke K; BIH Center for Regenerative Therapies and Institute of Medical Immunology, Charité Universitätsmedizin, Berlin, Germany.
Reipert BM; R&D Baxalta Innovations GmbH, part of Takeda, Vienna, Austria.
Horling F; R&D Baxalta Innovations GmbH, part of Takeda, Vienna, Austria.
Turecek PL; R&D Baxalta Innovations GmbH, part of Takeda, Vienna, Austria.

Front Immunol ; 13: 894411, 2022.

Article em En | MEDLINE | ID: mdl-35967311

Assuntos

Hemofilia A; Polietilenoglicóis; Animais; Hemofilia A/tratamento farmacológico; Humanos; Macrófagos/metabolismo; Mamíferos/metabolismo; Peso Molecular; Polietilenoglicóis/metabolismo; Proteínas Recombinantes/farmacologia; Proteínas Recombinantes/uso terapêutico

Palavras-chave

PEGylated recombinant coagulation factor VIII; monocyte-derived macrophages; polyethylene glycol; rurioctocog alfa pegol; vacuolation; vacuolization

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polietilenoglicóis / Hemofilia A Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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