Encapsulated bacteria deform lipid vesicles into flagellated swimmers.
Proc Natl Acad Sci U S A
; 119(34): e2206096119, 2022 08 23.
Article
em En
| MEDLINE
| ID: mdl-35969733
ABSTRACT
We study a synthetic system of motile Escherichia coli bacteria encapsulated inside giant lipid vesicles. Forces exerted by the bacteria on the inner side of the membrane are sufficient to extrude membrane tubes filled with one or several bacteria. We show that a physical coupling between the membrane tube and the flagella of the enclosed cells transforms the tube into an effective helical flagellum propelling the vesicle. We develop a simple theoretical model to estimate the propulsive force from the speed of the vesicles and demonstrate the good efficiency of this coupling mechanism. Together, these results point to design principles for conferring motility to synthetic cells.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Escherichia coli
/
Células Artificiais
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article