Prolonged FOS activity disrupts a global myogenic transcriptional program by altering 3D chromatin architecture in primary muscle progenitor cells.

Barutcu, A Rasim; Elizalde, Gabriel; Gonzalez, Alfredo E; Soni, Kartik; Rinn, John L; Wagers, Amy J; Almada, Albert E

Barutcu, A Rasim; Elizalde, Gabriel; Gonzalez, Alfredo E; Soni, Kartik; Rinn, John L; Wagers, Amy J; Almada, Albert E.

Afiliação

Barutcu AR; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.
Elizalde G; Present address: Donnelly Centre, University of Toronto, Toronto, ON, Canada.
Gonzalez AE; Department of Orthopaedic Surgery, University of Southern California, Los Angeles, CA, USA.
Soni K; Department of Stem Cell Biology and Regenerative Medicine, University of Southern California, Los Angeles, CA, USA.
Rinn JL; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.
Wagers AJ; Department of Orthopaedic Surgery, University of Southern California, Los Angeles, CA, USA.
Almada AE; Department of Stem Cell Biology and Regenerative Medicine, University of Southern California, Los Angeles, CA, USA.

Skelet Muscle ; 12(1): 20, 2022 08 15.

Article em En | MEDLINE | ID: mdl-35971133

Assuntos

Desenvolvimento Muscular; Mioblastos; Diferenciação Celular/fisiologia; Cromatina/genética; Fibras Musculares Esqueléticas; Células-Tronco

Palavras-chave

AP-1; FOS; Hi-C; Muscle progenitor cells; Muscle satellite cells; Myogenic differentiation; Topologically associated domains (TADs), gene loops

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenvolvimento Muscular / Mioblastos Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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