Combined TRIP13 and Aurora Kinase Inhibition Induces Apoptosis in Human Papillomavirus-Driven Cancers.

Ghosh, Soma; Mazumdar, Tuhina; Xu, Wei; Powell, Reid T; Stephan, Clifford; Shen, Li; Shah, Pooja A; Pickering, Curtis R; Myers, Jeffery N; Wang, Jing; Frederick, Mitchell J; Johnson, Faye M

Ghosh, Soma; Mazumdar, Tuhina; Xu, Wei; Powell, Reid T; Stephan, Clifford; Shen, Li; Shah, Pooja A; Pickering, Curtis R; Myers, Jeffery N; Wang, Jing; Frederick, Mitchell J; Johnson, Faye M.

Afiliação

Ghosh S; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Mazumdar T; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Xu W; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Powell RT; Center for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M College of Medicine, Houston, Texas.
Stephan C; Center for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M College of Medicine, Houston, Texas.
Shen L; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Shah PA; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Pickering CR; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Myers JN; The University of Texas Graduate School of Biomedical Sciences, Houston, Texas.
Wang J; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Frederick MJ; The University of Texas Graduate School of Biomedical Sciences, Houston, Texas.
Johnson FM; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Clin Cancer Res ; 28(20): 4479-4493, 2022 10 14.

Article em En | MEDLINE | ID: mdl-35972731

Assuntos

Alphapapillomavirus; Proteínas Oncogênicas Virais; Infecções por Papillomavirus; Neoplasias do Colo do Útero; ATPases Associadas a Diversas Atividades Celulares/metabolismo; ATPases Associadas a Diversas Atividades Celulares/farmacologia; ATPases Associadas a Diversas Atividades Celulares/uso terapêutico; Adenosina Trifosfatases; Apoptose; Aurora Quinases/metabolismo; Aurora Quinases/uso terapêutico; Proteínas de Ciclo Celular/genética; Proteínas de Ciclo Celular/metabolismo; Feminino; Humanos; Proteínas Oncogênicas Virais/genética; Papillomaviridae/genética; Proteínas E7 de Papillomavirus/genética; Infecções por Papillomavirus/complicações; Infecções por Papillomavirus/tratamento farmacológico; Infecções por Papillomavirus/genética; Proteína do Retinoblastoma/genética; Neoplasias do Colo do Útero/tratamento farmacológico; Neoplasias do Colo do Útero/genética; Neoplasias do Colo do Útero/patologia

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias do Colo do Útero / Proteínas Oncogênicas Virais / Infecções por Papillomavirus / Alphapapillomavirus Limite: Female / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google