Cutting Edge: Systemic Autoimmunity in Murine STAT3 Gain-of-Function Syndrome Is Characterized by Effector T Cell Expansion in the Absence of Overt Regulatory T Cell Dysfunction.

Woods, Jonathan; Pemberton, Sarah E; Largent, Andrea D; Chiang, Kristy; Liggitt, Denny; Oukka, Mohamed; Rawlings, David J; Jackson, Shaun W

Woods, Jonathan; Pemberton, Sarah E; Largent, Andrea D; Chiang, Kristy; Liggitt, Denny; Oukka, Mohamed; Rawlings, David J; Jackson, Shaun W.

Afiliação

Woods J; Seattle Children's Research Institute, Seattle, WA.
Pemberton SE; Seattle Children's Research Institute, Seattle, WA.
Largent AD; Seattle Children's Research Institute, Seattle, WA.
Chiang K; Seattle Children's Research Institute, Seattle, WA.
Liggitt D; Department of Comparative Medicine, University of Washington School of Medicine Seattle, WA.
Oukka M; Department of Immunology, University of Washington School of Medicine, Seattle, WA; and.
Rawlings DJ; Seattle Children's Research Institute, Seattle, WA.
Jackson SW; Department of Immunology, University of Washington School of Medicine, Seattle, WA; and.

J Immunol ; 209(6): 1033-1038, 2022 09 15.

Article em En | MEDLINE | ID: mdl-35995509

Assuntos

Autoimunidade; Fator de Transcrição STAT3; Linfócitos T Reguladores; Animais; Linfócitos T CD8-Positivos/metabolismo; Diferenciação Celular; Mutação com Ganho de Função; Técnicas de Introdução de Genes; Humanos; Inflamação/patologia; Camundongos; Camundongos Transgênicos; Fator de Transcrição STAT3/genética; Células Th17

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autoimunidade / Linfócitos T Reguladores / Fator de Transcrição STAT3 Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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