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Discovery of novel thiazolyl-pyrazolines as dual EGFR and VEGFR-2 inhibitors endowed with in vitro antitumor activity towards non-small lung cancer.
Abdelsalam, Esraa A; Abd El-Hafeez, Amer Ali; Eldehna, Wagdy M; El Hassab, Mahmoud A; Marzouk, Hala Mohamed M; Elaasser, Mahmoud M; Abou Taleb, Nageh A; Amin, Kamilia M; Abdel-Aziz, Hatem A; Ghosh, Pradipta; Hammad, Sherif F.
Afiliação
  • Abdelsalam EA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Helwan University, Cairo, Egypt.
  • Abd El-Hafeez AA; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.
  • Eldehna WM; Pharmacology and Experimental Oncology Unit, Department of Cancer Biology, National Cancer Institute, Cairo University, Cairo, Egypt.
  • El Hassab MA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
  • Marzouk HMM; School of Biotechnology, Badr University in Cairo, Badr City, Cairo, Egypt.
  • Elaasser MM; Department of Medicinal Chemistry, Faculty of Pharmacy, King Salman International University (KSIU), South Sinai, Egypt.
  • Abou Taleb NA; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.
  • Amin KM; Department of Biochemistry, Faculty of Medicine, Minia University, El-Minia, Egypt.
  • Abdel-Aziz HA; The Regional Center for Mycology and Biotechnology, Al-Azhar University, Cairo, Egypt.
  • Ghosh P; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Helwan University, Cairo, Egypt.
  • Hammad SF; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
J Enzyme Inhib Med Chem ; 37(1): 2265-2282, 2022 Dec.
Article em En | MEDLINE | ID: mdl-36000167
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Neoplasias Pulmonares / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Neoplasias Pulmonares / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article