Multi-Level Control of the ATM/ATR-CHK1 Axis by the Transcription Factor E4F1 in Triple-Negative Breast Cancer.

Batnini, Kalil; Houles, Thibault; Kirsh, Olivier; Du Manoir, Stanislas; Zaroual, Mehdi; Delpech, Hélène; Fallet, Chloé; Lacroix, Matthieu; Le Cam, Laurent; Theillet, Charles; Sardet, Claude; Rodier, Geneviève

Batnini, Kalil; Houles, Thibault; Kirsh, Olivier; Du Manoir, Stanislas; Zaroual, Mehdi; Delpech, Hélène; Fallet, Chloé; Lacroix, Matthieu; Le Cam, Laurent; Theillet, Charles; Sardet, Claude; Rodier, Geneviève.

Afiliação

Batnini K; Institut de Recherche en Cancérologie de Montpellier, IRCM U1194, Montpellier University, INSERM, ICM, CNRS, 34090 Montpellier, France.
Houles T; Institut de Recherche en Cancérologie de Montpellier, IRCM U1194, Montpellier University, INSERM, ICM, CNRS, 34090 Montpellier, France.
Kirsh O; Epigenetics and Cell Fate Team, CNRS, University Paris Cité, 75006 Paris, France.
Du Manoir S; Institut de Recherche en Cancérologie de Montpellier, IRCM U1194, Montpellier University, INSERM, ICM, CNRS, 34090 Montpellier, France.
Zaroual M; Institut de Recherche en Cancérologie de Montpellier, IRCM U1194, Montpellier University, INSERM, ICM, CNRS, 34090 Montpellier, France.
Delpech H; Institut de Recherche en Cancérologie de Montpellier, IRCM U1194, Montpellier University, INSERM, ICM, CNRS, 34090 Montpellier, France.
Fallet C; Institut de Recherche en Cancérologie de Montpellier, IRCM U1194, Montpellier University, INSERM, ICM, CNRS, 34090 Montpellier, France.
Lacroix M; Institut de Recherche en Cancérologie de Montpellier, IRCM U1194, Montpellier University, INSERM, ICM, CNRS, 34090 Montpellier, France.
Le Cam L; Institut de Recherche en Cancérologie de Montpellier, IRCM U1194, Montpellier University, INSERM, ICM, CNRS, 34090 Montpellier, France.
Theillet C; Institut de Recherche en Cancérologie de Montpellier, IRCM U1194, Montpellier University, INSERM, ICM, CNRS, 34090 Montpellier, France.
Sardet C; Institut de Recherche en Cancérologie de Montpellier, IRCM U1194, Montpellier University, INSERM, ICM, CNRS, 34090 Montpellier, France.
Rodier G; Institut de Recherche en Cancérologie de Montpellier, IRCM U1194, Montpellier University, INSERM, ICM, CNRS, 34090 Montpellier, France.

Int J Mol Sci ; 23(16)2022 Aug 16.

Article em En | MEDLINE | ID: mdl-36012478

Assuntos

Proteínas Repressoras; Fatores de Transcrição; Neoplasias de Mama Triplo Negativas; Ubiquitina-Proteína Ligases; Animais; Proteínas Mutadas de Ataxia Telangiectasia/metabolismo; Proteínas de Ciclo Celular/metabolismo; Quinase 1 do Ponto de Checagem/metabolismo; Dano ao DNA; Proteínas de Ligação a DNA/metabolismo; Humanos; Camundongos; Fosforilação; Proteínas Quinases/metabolismo; Proteínas Repressoras/metabolismo; Fatores de Transcrição/metabolismo; Neoplasias de Mama Triplo Negativas/metabolismo; Ubiquitina-Proteína Ligases/metabolismo

Palavras-chave

ATM/ATR-CHK checkpoint pathway; DNA Damage Response (DDR); E4F1 transcription factor; chemotherapy; triple-negative breast cancer

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Fatores de Transcrição / Ubiquitina-Proteína Ligases / Neoplasias de Mama Triplo Negativas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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