Investigation of the <i>N</i>-Glycosylation of the SARS-CoV-2 S Protein Contained in VLPs Produced in <i>Nicotiana benthamiana</i>.

Balieu, Juliette; Jung, Jae-Wan; Chan, Philippe; Lomonossoff, George P; Lerouge, Patrice; Bardor, Muriel

Investigation of the N-Glycosylation of the SARS-CoV-2 S Protein Contained in VLPs Produced in Nicotiana benthamiana.

Balieu, Juliette; Jung, Jae-Wan; Chan, Philippe; Lomonossoff, George P; Lerouge, Patrice; Bardor, Muriel.

Afiliação

Balieu J; Université de Rouen Normandie, Laboratoire GlycoMEV UR 4358, SFR Normandie Végétal FED 4277, Innovation Chimie Carnot, 76000 Rouen, France.
Jung JW; Department of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.
Chan P; Department of Molecular Biology, Jeonbuk National University, Jeonju 54896, Korea.
Lomonossoff GP; Université de Rouen Normandie, INSERM US 51, CNRS UAR 2026, HeRacLeS, 76000 Rouen, France.
Lerouge P; Department of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.
Bardor M; Université de Rouen Normandie, Laboratoire GlycoMEV UR 4358, SFR Normandie Végétal FED 4277, Innovation Chimie Carnot, 76000 Rouen, France.

Molecules ; 27(16)2022 Aug 11.

Article em En | MEDLINE | ID: mdl-36014368

Assuntos

COVID-19; SARS-CoV-2; Animais; Glicosilação; Humanos; Mamíferos/metabolismo; Polissacarídeos/química; SARS-CoV-2/genética; Glicoproteína da Espícula de Coronavírus; Nicotiana/genética; Nicotiana/metabolismo; Vírion

Palavras-chave

COVID; N-glycans; Nicotiana benthamiana; SPIKE; biologics; biopharmaceuticals; mass spectrometry; plant molecular farming; vaccine

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: SARS-CoV-2 / COVID-19 Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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