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Development of indole-2-carbonyl piperazine urea derivatives as selective FAAH inhibitors for efficient treatment of depression and pain.
Shang, Yanguo; Wang, Minghui; Hao, Qingjing; Meng, Tao; Li, Lili; Shi, Junwei; Yang, Guoqing; Zhang, Zhilan; Yang, Kan; Wang, Jinxin.
Afiliação
  • Shang Y; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal, Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
  • Wang M; Department of Chemistry, University of South Florida, Tampa, FL 33620, United States.
  • Hao Q; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal, Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
  • Meng T; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal, Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
  • Li L; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal, Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
  • Shi J; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal, Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China; Key Laboratory of Pharmaceutical Quality Control of Hebei Province, College of Pharmaceutical Sciences, Hebei University, Baoding 07
  • Yang G; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal, Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
  • Zhang Z; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal, Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
  • Yang K; Key Laboratory of Pharmaceutical Quality Control of Hebei Province, College of Pharmaceutical Sciences, Hebei University, Baoding 071002, China. Electronic address: yangkan1014@hbu.edu.cn.
  • Wang J; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal, Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China. Electronic address: jinxinwang@163.com.
Bioorg Chem ; 128: 106031, 2022 11.
Article em En | MEDLINE | ID: mdl-36037600
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ureia / Compostos Heterocíclicos Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ureia / Compostos Heterocíclicos Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article