Mitochondrial DNA is a major source of driver mutations in cancer.

Kim, Minsoo; Mahmood, Mahnoor; Reznik, Ed; Gammage, Payam A

Kim, Minsoo; Mahmood, Mahnoor; Reznik, Ed; Gammage, Payam A.

Afiliação

Kim M; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Mahmood M; CRUK Beatson Institute, Glasgow, UK.
Reznik E; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic
Gammage PA; CRUK Beatson Institute, Glasgow, UK; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK. Electronic address: p.gammage@beatson.gla.ac.uk.

Trends Cancer ; 8(12): 1046-1059, 2022 12.

Article em En | MEDLINE | ID: mdl-36041967

Assuntos

Genoma Mitocondrial; Neoplasias; Humanos; DNA Mitocondrial/genética; Mitocôndrias/genética; Mitocôndrias/metabolismo; Neoplasias/genética; Neoplasias/metabolismo; Mutação

Palavras-chave

cancer; genome editing; mitochondrial DNA; mutation selection

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Genoma Mitocondrial / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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