ADMET, Absorption, Distribution, Metabolism, Excretion, Toxicity; AI, Artificial Intelligence; BBB, Blood Brain Barrier; Biomarker; CS, Confidence Scores; DFT, Density Functional Theory; DL, Deep Learning; Docking; FEA, Functional Enrichment Analysis; GI, Gasto-Intestinal; GIN, Gene Interaction Network; GO, Gene Ontology; HOMO, Highest Occupied Molecular Orbital; IC, Inhibition Constant; LB, Lewy Bodies; LD, Lethal Dose; LUMO, Lowest Unoccupied Molecular Orbital; Ligand optimization; MDS, Molecular Dynamics Simulation; ML, Machine Learning; MMP, Mitochondrial Membrane Potential; Neurodegenerative disorder; PD, Parkinson's Disease; RMSD, Root Means Square Deviation; RMSF, Root Means Square Fluctuation; Rg, Radius of Gyration; SNpc, Substantia Nigra pars compacta; Simulation; Systems biology; TPSA, Total Polar Surface Area; UDCA, Ursodeoxycholic Acid