[Ascorbigen and its derivatives--depot preparations of ascorbic acid]. / Askorbigen i ego proizvodnye--depo-formy askorbinoboi kisloty.
Bioorg Khim
; 13(4): 539-45, 1987 Apr.
Article
em Ru
| MEDLINE
| ID: mdl-3606674
ABSTRACT
New derivatives of 2-C-/(indolyl-3)methyl/-beta-L-threo-L-glycero-3-hexulofuranosono- 1,4-lactone, vis. 1'-ethylascorbigen, 1'-benzylascorbigen and 1',2'-dimethyl-5'-methoxyascorbigen were obtained. In aquous solutions at physiological temperature and pH values ascorbigens disintegrate rather rapidly to yield L-ascorbic acid, the rate of the latter's formation depending on the substituent in the indole nucleus and increasing with growth of pH and temperature. Intraperitoneal injection of 1'-methylascorbigen to mice leads to steady rise of L-ascorbic acid level in blood plasma.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ácido Ascórbico
/
Indóis
Limite:
Animals
Idioma:
Ru
Ano de publicação:
1987
Tipo de documento:
Article