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Inducing mismatch repair deficiency sensitizes immune-cold neuroblastoma to anti-CTLA4 and generates broad anti-tumor immune memory.
El-Hajjar, Mikal; Gerhardt, Lara; Hong, Megan M Y; Krishnamoorthy, Mithunah; Figueredo, Rene; Zheng, Xiufen; Koropatnick, James; Maleki Vareki, Saman.
Afiliação
  • El-Hajjar M; Department of Microbiology and Immunology, Western University, London, ON, Canada; London Regional Cancer Program, Lawson Health Research Institute, London, ON, Canada.
  • Gerhardt L; Department of Pathology and Laboratory Medicine, Western University, London, ON, Canada.
  • Hong MMY; Department of Pathology and Laboratory Medicine, Western University, London, ON, Canada.
  • Krishnamoorthy M; Department of Pathology and Laboratory Medicine, Western University, London, ON, Canada.
  • Figueredo R; Department of Oncology, Western University, London, ON, Canada.
  • Zheng X; Department of Microbiology and Immunology, Western University, London, ON, Canada; Department of Pathology and Laboratory Medicine, Western University, London, ON, Canada; Department of Oncology, Western University, London, ON, Canada; Department of Surgery, Western University, London, ON, Canada.
  • Koropatnick J; Department of Microbiology and Immunology, Western University, London, ON, Canada; Department of Oncology, Western University, London, ON, Canada; London Regional Cancer Program, Lawson Health Research Institute, London, ON, Canada.
  • Maleki Vareki S; Department of Pathology and Laboratory Medicine, Western University, London, ON, Canada; Department of Oncology, Western University, London, ON, Canada; London Regional Cancer Program, Lawson Health Research Institute, London, ON, Canada. Electronic address: saman.malekivareki@lhsc.on.ca.
Mol Ther ; 31(2): 535-551, 2023 02 01.
Article em En | MEDLINE | ID: mdl-36068918
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Neoplasias Colorretais / Neuroblastoma Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Neoplasias Colorretais / Neuroblastoma Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article