Low Expression of Mitofusin 1 Gene Leads to Mitochondrial Dysfunction and Embryonic Genome Activation Failure in Ovine-Bovine Inter-Species Cloned Embryos.

Wu, Shanshan; Zhao, Xiaoyu; Wu, Meiling; Yang, Lei; Liu, Xuefei; Li, Danyi; Xu, Han; Zhao, Yuefang; Su, Xiaohu; Wei, Zhuying; Bai, Chunling; Su, Guanghua; Li, Guangpeng

Wu, Shanshan; Zhao, Xiaoyu; Wu, Meiling; Yang, Lei; Liu, Xuefei; Li, Danyi; Xu, Han; Zhao, Yuefang; Su, Xiaohu; Wei, Zhuying; Bai, Chunling; Su, Guanghua; Li, Guangpeng.

Afiliação

Wu S; State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock (R2BGL), Inner Mongolia University, 24 Zhaojun Rd., Hohhot 010070, China.
Zhao X; College of Life Sciences, Inner Mongolia University, 24 Zhaojun Rd., Hohhot 010070, China.
Wu M; State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock (R2BGL), Inner Mongolia University, 24 Zhaojun Rd., Hohhot 010070, China.
Yang L; College of Life Sciences, Inner Mongolia University, 24 Zhaojun Rd., Hohhot 010070, China.
Liu X; State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock (R2BGL), Inner Mongolia University, 24 Zhaojun Rd., Hohhot 010070, China.
Li D; College of Life Sciences, Inner Mongolia University, 24 Zhaojun Rd., Hohhot 010070, China.
Xu H; State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock (R2BGL), Inner Mongolia University, 24 Zhaojun Rd., Hohhot 010070, China.
Zhao Y; College of Life Sciences, Inner Mongolia University, 24 Zhaojun Rd., Hohhot 010070, China.
Su X; State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock (R2BGL), Inner Mongolia University, 24 Zhaojun Rd., Hohhot 010070, China.
Wei Z; College of Life Sciences, Inner Mongolia University, 24 Zhaojun Rd., Hohhot 010070, China.
Bai C; State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock (R2BGL), Inner Mongolia University, 24 Zhaojun Rd., Hohhot 010070, China.
Su G; College of Life Sciences, Inner Mongolia University, 24 Zhaojun Rd., Hohhot 010070, China.
Li G; State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock (R2BGL), Inner Mongolia University, 24 Zhaojun Rd., Hohhot 010070, China.

Int J Mol Sci ; 23(17)2022 Sep 04.

Article em En | MEDLINE | ID: mdl-36077543

Assuntos

Núcleo Celular; Embrião de Mamíferos; Trifosfato de Adenosina/metabolismo; Animais; Bovinos; Núcleo Celular/metabolismo; Clonagem de Organismos; Embrião de Mamíferos/metabolismo; Desenvolvimento Embrionário/genética; Feminino; Mitocôndrias/metabolismo; Técnicas de Transferência Nuclear; Oócitos/metabolismo; Gravidez; Espécies Reativas de Oxigênio/metabolismo; Ovinos/genética

Palavras-chave

embryonic genome activation; interspecies somatic cell nuclear transfer; mitochondrial fusion; transcriptomic sequencing

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Núcleo Celular / Embrião de Mamíferos Tipo de estudo: Prognostic_studies Limite: Animals / Pregnancy Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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