Reduction in Insulin Mediated ERK Phosphorylation by Palmitate in Liver Cells Is Independent of Fatty Acid Induced ER Stress.

Mubarak, Sindiyan Alshaikh; Otaibi, Abeer Al; Qarni, Ali Al; Bakillah, Ahmed; Iqbal, Jahangir

Mubarak, Sindiyan Alshaikh; Otaibi, Abeer Al; Qarni, Ali Al; Bakillah, Ahmed; Iqbal, Jahangir.

Afiliação

Mubarak SA; King Abdullah International Medical Research Center-Eastern Region, King Abdulaziz Hospital, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard-Health Affairs, Al-Ahsa 31982, Saudi Arabia.
Otaibi AA; King Abdullah International Medical Research Center-Eastern Region, King Abdulaziz Hospital, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard-Health Affairs, Al-Ahsa 31982, Saudi Arabia.
Qarni AA; King Abdullah International Medical Research Center-Eastern Region, King Abdulaziz Hospital, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard-Health Affairs, Al-Ahsa 31982, Saudi Arabia.
Bakillah A; King Abdullah International Medical Research Center-Eastern Region, King Abdulaziz Hospital, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard-Health Affairs, Al-Ahsa 31982, Saudi Arabia.
Iqbal J; King Abdullah International Medical Research Center-Eastern Region, King Abdulaziz Hospital, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard-Health Affairs, Al-Ahsa 31982, Saudi Arabia.

Nutrients ; 14(17)2022 Sep 02.

Article em En | MEDLINE | ID: mdl-36079898

Assuntos

Resistência à Insulina; Insulina; Estresse do Retículo Endoplasmático; MAP Quinases Reguladas por Sinal Extracelular/metabolismo; Ácidos Graxos/metabolismo; Glucose/metabolismo; Humanos; Insulina/metabolismo; Insulina/farmacologia; Fígado/metabolismo; Ácido Oleico/metabolismo; Ácido Oleico/farmacologia; Palmitatos/metabolismo; Palmitatos/farmacologia; Fosforilação; Proteínas Proto-Oncogênicas c-akt/metabolismo

Palavras-chave

ER stress; insulin resistance; insulin signaling; oleate; palmitate; tunicamycin; unfolded protein response

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Insulina Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google