A Patient-to-Model-to-Patient (PMP) Cancer Drug Discovery Protocol for Identifying and Validating Therapeutic Agents Targeting Tumor Regulatory Architecture.

Laise, Pasquale; Bosker, Gideon; Califano, Andrea; Alvarez, Mariano J

Laise, Pasquale; Bosker, Gideon; Califano, Andrea; Alvarez, Mariano J.

Afiliação

Laise P; DarwinHealth, New York, New York.
Bosker G; Department of Systems Biology, Columbia University Irving Medical Center, New York, New York.
Califano A; DarwinHealth, New York, New York.
Alvarez MJ; Department of Systems Biology, Columbia University Irving Medical Center, New York, New York.

Curr Protoc ; 2(9): e544, 2022 Sep.

Article em En | MEDLINE | ID: mdl-36083100

Assuntos

Antineoplásicos; Neoplasias; Antineoplásicos/farmacologia; Biomarcadores; Descoberta de Drogas; Humanos; Neoplasias/tratamento farmacológico; Estudos Prospectivos

Palavras-chave

biomarkers; cancer; drug discovery; regulatory networks; systems pharmacology

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias / Antineoplásicos Tipo de estudo: Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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