Oxidative stress-triggered pyroptosis mediates Candida albicans susceptibility in diabetic foot.

Chen, Nan; Deng, Jie; Zhang, Zhihui; Feng, Xia; Wang, Hongkang; Chen, Jian; Li, Ling; Cao, Yemin; Jia, Chenglin; Cao, Yongbing

Chen, Nan; Deng, Jie; Zhang, Zhihui; Feng, Xia; Wang, Hongkang; Chen, Jian; Li, Ling; Cao, Yemin; Jia, Chenglin; Cao, Yongbing.

Afiliação

Chen N; Institute of Vascular Anomalies, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200082, China.
Deng J; Institute of Vascular Anomalies, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200082, China.
Zhang Z; Institute of Vascular Anomalies, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200082, China.
Feng X; Institute of Vascular Anomalies, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200082, China.
Wang H; Department of Physiology and Pharmacology,School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Chen J; Institute of Vascular Anomalies, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200082, China.
Li L; Institute of Vascular Anomalies, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200082, China.
Cao Y; Institute of Vascular Anomalies, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200082, China.
Jia C; Institute of Vascular Anomalies, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200082, China. Electronic address: jiachenglin0716@126.com.
Cao Y; Institute of Vascular Anomalies, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200082, China. Electronic address: ybcao@vip.sina.com.

Microb Pathog ; 172: 105765, 2022 Nov.

Article em En | MEDLINE | ID: mdl-36087690

Assuntos

Diabetes Mellitus Experimental; Pé Diabético; Animais; Camundongos; Piroptose/fisiologia; Inflamassomos/metabolismo; Proteína 3 que Contém Domínio de Pirina da Família NLR/genética; Proteína 3 que Contém Domínio de Pirina da Família NLR/metabolismo; Candida albicans/metabolismo; NF-kappa B/metabolismo; Diabetes Mellitus Experimental/complicações; Caspase 1/metabolismo; Estresse Oxidativo/fisiologia; Citocinas/metabolismo; Fatores de Transcrição Forkhead/metabolismo

Palavras-chave

Apoptosis; Candida albicans; Diabetic infections; NLRP3; Oxidative stress; Pyroptosis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pé Diabético / Diabetes Mellitus Experimental Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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