Two New C18 -Diterpenoid Alkaloids from Aconitum leucostomum Worosch.
Chem Biodivers
; 19(10): e202200483, 2022 Oct.
Article
em En
| MEDLINE
| ID: mdl-36094326
ABSTRACT
Two new lappaconitine-type C18 -diterpenoid alkaloids, named as leucostosines C (1) and D (2), together with six known compounds (3-8), were isolated from the roots of Aconitum leucostomum Worosch. Their structures were elucidated by various spectroscopic analyses, including IR, HR-ESI-MS, NMR spectra and X-ray experiments. Leucostosine C is the first diterpenoid alkaloid bearing the 7-amino group. The isolated compounds were tested for the acetylcholinesterase (AChE) inhibitory effect and neuroprotective activity, none of them showed significant activities.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Aconitum
/
Diterpenos
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Alcaloides
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article