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Increased p53 expression induced by APR-246 reprograms tumor-associated macrophages to augment immune checkpoint blockade.
Ghosh, Arnab; Michels, Judith; Mezzadra, Riccardo; Venkatesh, Divya; Dong, Lauren; Gomez, Ricardo; Samaan, Fadi; Ho, Yu-Jui; Campesato, Luis Felipe; Mangarin, Levi; Fak, John; Suek, Nathan; Holland, Aliya; Liu, Cailian; Abu-Akeel, Mohsen; Bykov, Yonina; Zhong, Hong; Fitzgerald, Kelly; Budhu, Sadna; Chow, Andrew; Zappasodi, Roberta; Panageas, Katherine S; de Henau, Olivier; Ruscetti, Marcus; Lowe, Scott W; Merghoub, Taha; Wolchok, Jedd D.
Afiliação
  • Ghosh A; Swim Across America and Ludwig Collaborative Laboratory, Immunology Program, Parker Institute for Cancer Immunotherapy.
  • Michels J; Immuno-Oncology Service, Human Oncology and Pathogenesis Program.
  • Mezzadra R; Department of Medicine, and.
  • Venkatesh D; Swim Across America and Ludwig Collaborative Laboratory, Immunology Program, Parker Institute for Cancer Immunotherapy.
  • Dong L; Immuno-Oncology Service, Human Oncology and Pathogenesis Program.
  • Gomez R; Department of Cancer Biology and Genetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Samaan F; Swim Across America and Ludwig Collaborative Laboratory, Immunology Program, Parker Institute for Cancer Immunotherapy.
  • Ho YJ; Immuno-Oncology Service, Human Oncology and Pathogenesis Program.
  • Campesato LF; Swim Across America and Ludwig Collaborative Laboratory, Immunology Program, Parker Institute for Cancer Immunotherapy.
  • Mangarin L; Immuno-Oncology Service, Human Oncology and Pathogenesis Program.
  • Fak J; Swim Across America and Ludwig Collaborative Laboratory, Immunology Program, Parker Institute for Cancer Immunotherapy.
  • Suek N; Immuno-Oncology Service, Human Oncology and Pathogenesis Program.
  • Holland A; Swim Across America and Ludwig Collaborative Laboratory, Immunology Program, Parker Institute for Cancer Immunotherapy.
  • Liu C; Immuno-Oncology Service, Human Oncology and Pathogenesis Program.
  • Abu-Akeel M; Department of Cancer Biology and Genetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Bykov Y; Swim Across America and Ludwig Collaborative Laboratory, Immunology Program, Parker Institute for Cancer Immunotherapy.
  • Zhong H; Immuno-Oncology Service, Human Oncology and Pathogenesis Program.
  • Fitzgerald K; Swim Across America and Ludwig Collaborative Laboratory, Immunology Program, Parker Institute for Cancer Immunotherapy.
  • Budhu S; Immuno-Oncology Service, Human Oncology and Pathogenesis Program.
  • Chow A; Rockefeller University, New York, New York, USA.
  • Zappasodi R; Swim Across America and Ludwig Collaborative Laboratory, Immunology Program, Parker Institute for Cancer Immunotherapy.
  • Panageas KS; Immuno-Oncology Service, Human Oncology and Pathogenesis Program.
  • de Henau O; Swim Across America and Ludwig Collaborative Laboratory, Immunology Program, Parker Institute for Cancer Immunotherapy.
  • Ruscetti M; Immuno-Oncology Service, Human Oncology and Pathogenesis Program.
  • Lowe SW; Swim Across America and Ludwig Collaborative Laboratory, Immunology Program, Parker Institute for Cancer Immunotherapy.
  • Merghoub T; Immuno-Oncology Service, Human Oncology and Pathogenesis Program.
  • Wolchok JD; Swim Across America and Ludwig Collaborative Laboratory, Immunology Program, Parker Institute for Cancer Immunotherapy.
J Clin Invest ; 132(18)2022 09 15.
Article em En | MEDLINE | ID: mdl-36106631
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores de Checkpoint Imunológico / Macrófagos Associados a Tumor Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores de Checkpoint Imunológico / Macrófagos Associados a Tumor Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article