UDP-glucose dehydrogenase (UGDH) activity is suppressed by peroxide and promoted by PDGF in fibroblast-like synoviocytes: Evidence of a redox control mechanism.

Chandrasekaran, Ramya; Mathieu, Colleen; Sheth, Rishi; Cheng, Alexandre P; Fong, David; McCormack, Robert; El-Gabalawy, Hani; Alishetty, Suman; Paige, Mikell; Hoemann, Caroline D

Chandrasekaran, Ramya; Mathieu, Colleen; Sheth, Rishi; Cheng, Alexandre P; Fong, David; McCormack, Robert; El-Gabalawy, Hani; Alishetty, Suman; Paige, Mikell; Hoemann, Caroline D.

Afiliação

Chandrasekaran R; Department of Bioengineering, George Mason University, Manassas, Virginia, United States of America.
Mathieu C; Institute of Biomedical Engineering, Polytechnique Montréal, Montréal, QC, Canada.
Sheth R; Department of Chemical Engineering, Polytechnique Montréal, Montréal, QC, Canada.
Cheng AP; Department of Bioengineering, George Mason University, Manassas, Virginia, United States of America.
Fong D; Department of Chemical Engineering, Polytechnique Montréal, Montréal, QC, Canada.
McCormack R; Institute of Biomedical Engineering, Polytechnique Montréal, Montréal, QC, Canada.
El-Gabalawy H; Department of Orthopedic Surgery, University of British Columbia, Vancouver, BC, Canada.
Alishetty S; Department of Medicine and Immunology, University of Manitoba, Winnipeg, MB, Canada.
Paige M; Department of Bioengineering, George Mason University, Manassas, Virginia, United States of America.
Hoemann CD; Department of Chemistry & Biochemistry, George Mason University, Manassas, Virginia, United States of America.

PLoS One ; 17(9): e0274420, 2022.

Article em En | MEDLINE | ID: mdl-36107941

Assuntos

Sinoviócitos; Animais; Cisteína/metabolismo; Fibroblastos/metabolismo; Formazans; Glucose/farmacologia; Glucose Desidrogenase/metabolismo; Glutationa/metabolismo; Glutationa Redutase/metabolismo; Humanos; Ácido Hialurônico/metabolismo; Ácido Hialurônico/farmacologia; Maleimidas; NAD/metabolismo; Nitroazul de Tetrazólio; Oxirredução; Peróxidos; Coelhos; Sinoviócitos/metabolismo; Fator de Crescimento Transformador beta1/metabolismo; Difosfato de Uridina/metabolismo; Uridina Difosfato Glucose Desidrogenase/química; Uridina Difosfato Glucose Desidrogenase/metabolismo; Xilose

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sinoviócitos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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