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Dual Fc optimization to increase the cytotoxic activity of a CD19-targeting antibody.
Gehlert, Carina Lynn; Rahmati, Pegah; Boje, Ammelie Svea; Winterberg, Dorothee; Krohn, Steffen; Theocharis, Thomas; Cappuzzello, Elisa; Lux, Anja; Nimmerjahn, Falk; Ludwig, Ralf J; Lustig, Marta; Rösner, Thies; Valerius, Thomas; Schewe, Denis Martin; Kellner, Christian; Klausz, Katja; Peipp, Matthias.
Afiliação
  • Gehlert CL; Division of Antibody-Based Immunotherapy, Department of Medicine II, Christian Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.
  • Rahmati P; Division of Antibody-Based Immunotherapy, Department of Medicine II, Christian Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.
  • Boje AS; Division of Antibody-Based Immunotherapy, Department of Medicine II, Christian Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.
  • Winterberg D; Department of Pediatrics I, University Hospital Schleswig-Holstein and Christian-Albrechts-University Kiel, Kiel, Germany.
  • Krohn S; Division of Antibody-Based Immunotherapy, Department of Medicine II, Christian Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.
  • Theocharis T; Division of Antibody-Based Immunotherapy, Department of Medicine II, Christian Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.
  • Cappuzzello E; Oncology and Immunology Section, Department of Surgery Oncology and Gastroenterology, University of Padova, Padova, Italy.
  • Lux A; Division of Genetics, Department of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
  • Nimmerjahn F; Division of Genetics, Department of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
  • Ludwig RJ; Lübeck Institute of Experimental Dermatology, University of Lübeck, Lübeck, Germany.
  • Lustig M; Division of Stem Cell Transplantation and Immunotherapy Department of Medicine II, Christian Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.
  • Rösner T; Division of Stem Cell Transplantation and Immunotherapy Department of Medicine II, Christian Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.
  • Valerius T; Division of Stem Cell Transplantation and Immunotherapy Department of Medicine II, Christian Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.
  • Schewe DM; Department of Pediatrics, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
  • Kellner C; Division of Transfusion Medicine, Cell Therapeutics and Haemostaseology, Ludwig-Maximilians-University (LMU) University Hospital Munich, Munich, Germany.
  • Klausz K; Division of Antibody-Based Immunotherapy, Department of Medicine II, Christian Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.
  • Peipp M; Division of Antibody-Based Immunotherapy, Department of Medicine II, Christian Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.
Front Immunol ; 13: 957874, 2022.
Article em En | MEDLINE | ID: mdl-36119088
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de IgG / Citotoxicidade Celular Dependente de Anticorpos Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de IgG / Citotoxicidade Celular Dependente de Anticorpos Idioma: En Ano de publicação: 2022 Tipo de documento: Article