Obesity-induced miR-802 directly targets AMPK and promotes nonalcoholic steatohepatitis in mice.

Sun, Hao; Seok, Sunmi; Jung, Hyunkyung; Kemper, Byron; Kemper, Jongsook Kim

Sun, Hao; Seok, Sunmi; Jung, Hyunkyung; Kemper, Byron; Kemper, Jongsook Kim.

Afiliação

Sun H; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.
Seok S; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.
Jung H; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.
Kemper B; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.
Kemper JK; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA. Electronic address: jongsook@illinois.edu.

Mol Metab ; 66: 101603, 2022 12.

Article em En | MEDLINE | ID: mdl-36126896

Assuntos

MicroRNAs; Hepatopatia Gordurosa não Alcoólica; Camundongos; Humanos; Animais; Hepatopatia Gordurosa não Alcoólica/metabolismo; Proteínas Quinases Ativadas por AMP; Camundongos Endogâmicos C57BL; Obesidade/metabolismo; Camundongos Obesos; MicroRNAs/genética; MicroRNAs/metabolismo

Palavras-chave

FXR; Hepatocellular apoptosis; Inflammation; NAFLD; NASH; OCA

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MicroRNAs / Hepatopatia Gordurosa não Alcoólica Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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