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Insight into mode-of-action and structural determinants of the compstatin family of clinical complement inhibitors.
Lamers, Christina; Xue, Xiaoguang; Smiesko, Martin; van Son, Henri; Wagner, Bea; Berger, Nadja; Sfyroera, Georgia; Gros, Piet; Lambris, John D; Ricklin, Daniel.
Afiliação
  • Lamers C; Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
  • Xue X; Institute of Drug Discovery, Faculty of Medicine, Leipzig University, Brüderstrasse 34, 04103, Leipzig, Germany.
  • Smiesko M; Department of Chemistry, Faculty of Science, Utrecht University, Padualaan 8, 3584, Utrecht, The Netherlands.
  • van Son H; Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
  • Wagner B; Department of Chemistry, Faculty of Science, Utrecht University, Padualaan 8, 3584, Utrecht, The Netherlands.
  • Berger N; Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
  • Sfyroera G; Department of Pathology & Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, 401 Stellar Chance, 422 Curie Blvd, Philadelphia, 19104, PA, USA.
  • Gros P; Department of Pathology & Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, 401 Stellar Chance, 422 Curie Blvd, Philadelphia, 19104, PA, USA.
  • Lambris JD; Department of Chemistry, Faculty of Science, Utrecht University, Padualaan 8, 3584, Utrecht, The Netherlands.
  • Ricklin D; Department of Pathology & Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, 401 Stellar Chance, 422 Curie Blvd, Philadelphia, 19104, PA, USA. lambris@pennmedicine.upenn.edu.
Nat Commun ; 13(1): 5519, 2022 09 20.
Article em En | MEDLINE | ID: mdl-36127336
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complemento C3 / Inativadores do Complemento Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complemento C3 / Inativadores do Complemento Idioma: En Ano de publicação: 2022 Tipo de documento: Article