CD44-targeted nanoparticles with GSH-responsive activity as powerful therapeutic agents against breast cancer.

Brindisi, Matteo; Curcio, Manuela; Frattaruolo, Luca; Cirillo, Giuseppe; Leggio, Antonella; Rago, Vittoria; Nicoletta, Fiore Pasquale; Cappello, Anna Rita; Iemma, Francesca

Brindisi, Matteo; Curcio, Manuela; Frattaruolo, Luca; Cirillo, Giuseppe; Leggio, Antonella; Rago, Vittoria; Nicoletta, Fiore Pasquale; Cappello, Anna Rita; Iemma, Francesca.

Afiliação

Brindisi M; Cell Adhesion Unit, San Raffaele Vita-Salute University, 20132 Milan, Italy; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, CS, Italy.
Curcio M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, CS, Italy. Electronic address: manuela.curcio@unical.it.
Frattaruolo L; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, CS, Italy.
Cirillo G; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, CS, Italy.
Leggio A; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, CS, Italy.
Rago V; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, CS, Italy.
Nicoletta FP; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, CS, Italy.
Cappello AR; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, CS, Italy. Electronic address: annarita.cappello@unical.it.
Iemma F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, CS, Italy.

Int J Biol Macromol ; 221: 1491-1503, 2022 Nov 30.

Article em En | MEDLINE | ID: mdl-36130642

Assuntos

Neoplasias da Mama; Nanopartículas; Humanos; Feminino; Neoplasias da Mama/tratamento farmacológico; Neoplasias da Mama/patologia; Ácido Hialurônico/uso terapêutico; Doxorrubicina/farmacologia; Doxorrubicina/uso terapêutico; Linhagem Celular Tumoral; Receptores de Hialuronatos

Palavras-chave

Breast cancer; CD44 receptors; GSH-responsive; HA-HSA conjugate; Metastasis process; Targeted nanoparticles

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Nanopartículas Limite: Female / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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