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Effect of capmatinib on the pharmacokinetics of substrates of CYP3A (midazolam) and CYP1A2 (caffeine) in patients with MET-dysregulated solid tumours.
Chen, Xinhui; Isambert, Nicolas; López-López, Rafael; Giovannini, Monica; Pognan, Nathalie; Kapoor, Shruti; Quinlan, Michelle; You, Benoit; Cui, Xiaoming; Rahmanzadeh, Gholamreza; Mau-Sorensen, Morten.
Afiliação
  • Chen X; Novartis Institutes for BioMedical Research, East Hanover, New Jersey, USA.
  • Isambert N; Department of Medical Oncology, Centre Georges-François Leclerc, Dijon, France.
  • López-López R; Medical Oncology, University Clinical Hospital-IDIS-CIBERONC, Santiago de Compostela, Spain.
  • Giovannini M; Global Drug Development, Novartis Services Inc., Princeton, New Jersey, USA.
  • Pognan N; Global Drug Development, Novartis Pharma S.A.S., Rueil-Malmaison, France.
  • Kapoor S; Global Drug Development, Novartis Services Inc., Princeton, New Jersey, USA.
  • Quinlan M; Global Drug Development, Novartis Services Inc., Princeton, New Jersey, USA.
  • You B; Medical Oncology, Institut de Cancérologie des Hospices Civils de Lyon, Université Claude Bernard Lyon 1, Cicly, Gineco, Lyon, France.
  • Cui X; Novartis Institutes for BioMedical Research, East Hanover, New Jersey, USA.
  • Rahmanzadeh G; Novartis Pharma AG, Basel, Switzerland.
  • Mau-Sorensen M; Department of Oncology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Br J Clin Pharmacol ; 89(3): 1046-1055, 2023 03.
Article em En | MEDLINE | ID: mdl-36131603
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cafeína / Citocromo P-450 CYP1A2 Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cafeína / Citocromo P-450 CYP1A2 Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article